2-Hydroxy-8-methoxy-3-methyl-1-naphthalenecarboxylic Acid Methyl Ester CAS 128425-37-6

Purity 97%+In StockPharmaceutical Standards
CAS No.128425-37-6
Molecular FormulaC14H14O4
Molecular Weight246.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Hydroxy-8-methoxy-3-methyl-1-naphthalenecarboxylic Acid Methyl Ester CAS 128425-37-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Hydroxy-8-methoxy-3-methyl-1-naphthalenecarboxylic Acid Methyl Ester.

CATO supplies 2-Hydroxy-8-methoxy-3-methyl-1-naphthalenecarboxylic Acid Methyl Ester (CAS 128425-37-6), a certified reference material (molecular formula C14H14O4, MW 246.26 g/mol) for analytical method development and quality control.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, 2-Hydroxy-8-methoxy-3-methyl-1-naphthalenecarboxylic Acid Methyl Ester is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H14O4
Molecular Weight246.26 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993

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