5-Chloro-4-formyl-1-methyl-3-(trifluoromethyl)-1H-pyrazole CAS 128455-62-9
| CAS No. | 128455-62-9 |
| Molecular Formula | C6H4ClF3N2O |
| Molecular Weight | 212.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-Chloro-4-formyl-1-methyl-3-(trifluoromethyl)-1H-pyrazole (CAS 128455-62-9), molecular formula C6H4ClF3N2O and molecular weight 212.56 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 5-Chloro-4-formyl-1-methyl-3-(trifluoromethyl)-1H-pyrazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 212.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF3N2O |
| Molecular Weight | 212.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-6-(2,2,2-trifluoroethoxy)pyrazine (CAS 1016530-98-5)
- 2-Chloro-3-(trifluoromethoxy)pyridin-4-amine (CAS 1221171-79-4)
- 2-Chloro-6-(trifluoromethoxy)pyridin-4-amine (CAS 1221171-99-8)
- 2-Chloro-3-(2,2,2-trifluoroethoxy)pyrazine (CAS 1251156-39-4)
- 2-Chloro-4-methoxy-5-(trifluoromethyl)pyrimidine (CAS 1312535-76-4)
- 3-Chloro-5-(2,2,2-trifluoroethoxy)pyridazine (CAS 1346691-33-5)
- 3-Chloro-5-(trifluoromethoxy)pyridin-2-amine (CAS 1361852-64-3)
- 2-Chloro-5-(trifluoromethoxy)pyridin-4-amine (CAS 1361890-39-2)
Recommended Standards
- 1-Methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride (CAS 126674-98-4)
- 1-Methyl-3-(trifluoromethyl)-1h-pyrazole-5-carbonyl chloride (CAS 129768-24-7)
- 2-(Chloromethyl)-6-(trifluoromethyl)pyrimidin-4-ol (CAS 1240596-45-5)
- 2-Chloro-4-methoxy-6-(trifluoromethyl)pyrimidine (CAS 1402551-64-7)
- 1,2-Dibromo-3-difluoromethoxy-5-(trifluoromethylthio)benzene (CAS 1803775-20-3)
- 4-(2-Bromophenoxy)-3-methylaniline (CAS 1152877-43-4)
- 7-Fluoro-2-methyl-2,3-dihydrobenzofuran-3-amine (CAS 1248408-36-7)
- 4-(2-Hydroxypropan-2-yl)benzonitrile (CAS 77802-22-3)
- 2-((2-Chlorothiazol-5-yl)methoxy)isoindoline-1,3-dione (CAS 339018-42-7)
- 2-(6-(Dimethylamino)-5-methylpyridin-3-yl)pyrrolidine-1-carbaldehyde (CAS 1352499-62-7)
- (2-Chloro-4-(piperidine-1-carbonyl)phenyl)boronic acid (CAS 1451392-96-3)
- 11-Deoxyalisol B (CAS 155073-73-7)
- 1-(Tert-butoxycarbonyl)-4-(3-methoxyphenyl)piperidine-4-carboxylic acid (CAS 1158750-63-0)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com