Rivastigmine Impurity 44 CAS 1285033-79-5
| CAS No. | 1285033-79-5 |
| Molecular Formula | C16H18O3 |
| Molecular Weight | 258.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Rivastigmine Impurity 44 (CAS 1285033-79-5, C16H18O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Rivastigmine Impurity 44 (C16H18O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Rivastigmine Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H18O3 |
| Molecular Weight | 258.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
Related Rivastigmine Standards
- Rivastigmine Impurity 41 (CAS CATO-C4X-138441)
- Rivastigmine –D6 (Racemic mixture) (CAS 194930-04-6)
- Rivastigmine-d5 (CAS 1133229-22-7)
- Rivastigmine Benzyl Impurity (CAS 1111083-50-1)
- Rivastigmine-d3 (CAS 1133229-21-6)
- Rivastigmine Diethyl Analog (CAS 1230021-34-7)
- Rivastigmine impurity 32 (CAS CATO-C4X-138432)
- Rivastigmine impurity 35 (CAS CATO-C4X-138435)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com