4-[(3-Fluoro-2-nitrophenoxy)methyl]piperidine hydrochloride CAS 1286272-66-9
| CAS No. | 1286272-66-9 |
| Molecular Formula | C12H15FN2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 290.72 g/mol gives 4-[(3-Fluoro-2-nitrophenoxy)methyl]piperidine hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-[(3-Fluoro-2-nitrophenoxy)methyl]piperidine hydrochloride (CAS 1286272-66-9), a certified reference material (molecular formula C12H15FN2O3HCl, MW 290.72 g/mol) for analytical method development and quality control.
The molecular framework of 4-[(3-Fluoro-2-nitrophenoxy)methyl]piperidine hydrochloride (C12H15FN2O3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[(3-Fluoro-2-nitrophenoxy)methyl]piperidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15FN2O3 HCl |
| Molecular Weight | 290.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-[(2-Fluoro-4-nitrophenoxy)methyl]-1-methylpiperidine (CAS 1000052-54-9)
- 3-Fluoro-4-((1-methylpiperidin-4-yl)methoxy)aniline (CAS 1000053-56-4)
- 2-Fluoro-5-iodo-4-methoxybenzoic acid (CAS 1000162-78-6)
- Ethyl 4-fluoro-3-ethoxybenzoate (CAS 1000207-63-5)
- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
- 2-Fluoro-3-hydroxybenzonitrile (CAS 1000339-24-1)
- 1-(5-Fluoro-2-methylphenyl)pyrrolidine (CAS 1000339-32-1)
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- (R)-2-(4-methyl-3-nitrophenyl)pyrrolidine (CAS 1212972-05-8)
- 5-Acetyl-4-amino-2,6-dimethylpyridazin-3(2H)-one (CAS 175135-90-7)
- n,n'-(Methylenebis(4,1-phenylene))bis(aziridine-1-carboxamide) (CAS 7417-99-4)
- 5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole (CAS 1352734-32-7)
- Tofacitinib Base (CAS 477600-75-2)
- 5-(O-tolyl)-1,3,4-oxadiazol-2-amine (CAS 1750-78-3)
- 3-Ethylpicolinaldehyde (CAS 98491-40-8)
- p-Tolyl benzenesulfonate (CAS 5398-09-4)
- 4-(4-Chlorobenzyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid (CAS 1146291-70-4)
- Neuropeptide AF (human) (CAS 192387-38-5)
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