1-(5-Fluoro-2-methoxybenzyl)piperidin-4-amine dihydrochloride CAS 1286273-08-2
| CAS No. | 1286273-08-2 |
| Molecular Formula | C13H19FN2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(5-Fluoro-2-methoxybenzyl)piperidin-4-amine dihydrochloride (C13H19FN2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(5-Fluoro-2-methoxybenzyl)piperidin-4-amine dihydrochloride (CAS 1286273-08-2) is a high-purity analytical reference standard with the molecular formula C13H19FN2OHCl and a molecular weight of 274.76 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(5-Fluoro-2-methoxybenzyl)piperidin-4-amine dihydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H19FN2O 2*HCl |
| Molecular Weight | 274.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-[(2-Fluoro-4-nitrophenoxy)methyl]-1-methylpiperidine (CAS 1000052-54-9)
- 3-Fluoro-4-((1-methylpiperidin-4-yl)methoxy)aniline (CAS 1000053-56-4)
- 2-Fluoro-5-iodo-4-methoxybenzoic acid (CAS 1000162-78-6)
- Ethyl 4-fluoro-3-ethoxybenzoate (CAS 1000207-63-5)
- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
- 2-Fluoro-3-hydroxybenzonitrile (CAS 1000339-24-1)
- 1-(5-Fluoro-2-methylphenyl)pyrrolidine (CAS 1000339-32-1)
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- 5-Chloro-2-ethylbenzoic acid (CAS 17746-68-8)
- tert-Butyl 4-hydroxy-4-methyl-1,4-bipiperidine-1-carboxylate (CAS 438208-24-3)
- tert-butyl 3-[(fluorosulfonyl)methyl]pyrrolidine-1-carboxylate (CAS 1955520-31-6)
- 1-Ethylpiperidine phosphinate (CAS 145060-63-5)
- 3-(4-((Benzyloxy)carbonyl)piperazin-1-yl)propanoic acid (CAS 1156305-81-5)
- 2-Chloro-4-(tetrahydro-2H-pyran-4-yloxy)pyrimidine (CAS 1216402-53-7)
- 3-(4-Chlorophenyl)-7-(furan-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 866049-98-1)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3,4-dichlorophenyl)acetamide (CAS 476486-06-3)
- 2-Azido-1-pivaloyl D-erythro-Sphingosine (CAS 114275-41-1)
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