(4-(Trifluoromethoxy)pyrrolidin-2-yl)methanol CAS 1286743-77-8
| CAS No. | 1286743-77-8 |
| Molecular Formula | C6H10F3NO2 |
| Molecular Weight | 185.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (4-(Trifluoromethoxy)pyrrolidin-2-yl)methanol is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(4-(Trifluoromethoxy)pyrrolidin-2-yl)methanol (CAS 1286743-77-8) is a high-purity analytical reference standard with the molecular formula C6H10F3NO2 and a molecular weight of 185.14 g/mol.
The molecular framework of (4-(Trifluoromethoxy)pyrrolidin-2-yl)methanol (C6H10F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (4-(Trifluoromethoxy)pyrrolidin-2-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10F3NO2 |
| Molecular Weight | 185.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 6-(trifluoromethoxy)pyridin-3-ol (CAS 1361494-43-0)
- 3-(Trifluoromethoxy)azetidine-3-carboxylic acid (CAS 1638920-43-0)
- 6-(trifluoromethoxy)pyridin-2-amine (CAS 1131007-45-8)
- 4-(trifluoromethoxy)pyridin-2-amine (CAS 1206980-54-2)
- 3-(trifluoromethoxy)pyridin-2-amine (CAS 1206981-49-8)
- 5-(trifluoromethoxy)pyridin-2-amine (CAS 1221171-88-5)
- 2-(cis-3-(Trifluoromethoxy)cyclobutyl)ethan-1-ol (CAS 2489409-56-3)
- 3-(Trifluoromethoxy)cyclohexan-1-ol (CAS 2092719-06-5)
Recommended Standards
- 2,2,2-Trifluoro-N-(4-hydroxybutyl)acetamide (CAS 128238-43-7)
- 2-(5-Amino-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)acetic acid (CAS 1341717-74-5)
- 2-Amino-3-methyl-2-(trifluoromethyl)butanoic acid (CAS 127048-24-2)
- Methyl (3,3,3-trifluoropropyl)glycinate (CAS 1343757-79-8)
- (4,6-dimethyl-1,3-phenylene)dimethanol (CAS 7371-81-5)
- Rotigotine Sulfate (CAS 128478-69-3)
- 6-Bromo-1h-pyrazolo[3,4-b]pyridine-3-carboxylicacid (CAS 1782248-22-9)
- 2-Methyl-2-((tetrahydro-2H-thiopyran-4-yl)amino)pentanoic acid (CAS 1467124-44-2)
- 1-cyclopropyl-2-(2-methylphenyl)ethan-1-one (CAS 56594-99-1)
- 3,5-Diethoxy-4-(1H-pyrrol-1-yl)benzaldehyde (CAS 909853-89-0)
- 2-C-Methylguanosine (CAS 374750-30-8)
- Bicyclo[2.2.1]heptan-1-ylmethanamine (CAS 70379-44-1)
- Ethyl 5-(5-chlorothiophen-2-yl)isoxazole-3-carboxylate (CAS 323594-72-5)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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