(2E)-1-(4-Bromophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one CAS 1287203-24-0
| CAS No. | 1287203-24-0 |
| Molecular Formula | C18H17BrO4 |
| Molecular Weight | 377.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2E)-1-(4-Bromophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (CAS 1287203-24-0), molecular formula C18H17BrO4 and molecular weight 377.23 g/mol, is a CATO reference standard with documented purity and traceability.
(2E)-1-(4-Bromophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (C18H17BrO4) contains a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2E)-1-(4-Bromophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17BrO4 |
| Molecular Weight | 377.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
Related E Standards
- 8-(4-Bromophenyl)-6,7-dimethyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-ol (CAS 1212202-17-9)
- (2E)-1-(3-Bromophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (CAS 1287257-13-9)
- (2E)-1-(3-Bromophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 358656-15-2)
- (2E)-1-(4-Bromophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 284488-41-1)
- (3Z)-3-[(4-Bromophenyl)imino]-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 445455-69-6)
- 5-(4-Bromophenyl)-N-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine (CAS 827580-48-3)
- N-(4-Bromophenyl)-5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine (CAS 827580-67-6)
- 1-(4-Bromophenyl)-3-((4-fluorobenzyl)amino)pyrrolidine-2,5-dione (CAS 355134-73-5)
Recommended Standards
- (E)-3-(3-bromo-4-methoxyphenyl)-1-(2,4-dimethoxyphenyl)prop-2-en-1-one (CAS 1228275-91-9)
- Methyl 4-((4-(2-bromopropanoyl)phenoxy)methyl)benzoate (CAS 1547067-07-1)
- 5-Bromo-4-(n-(5-methylpyridin-2-yl)sulfamoyl)thiophene-2-carboxylic acid (CAS 1098390-79-4)
- ((2-Acetamido-5-bromophenyl)(phenyl)methyl)glycine (CAS 313226-04-9)
- n-(5-Amino-2-methylphenyl)pyridine-4-carboxamide (CAS 436089-25-7)
- (R)-3,3'-Diiodo-[1,1'-binaphthalene]-2,2'-diol (CAS 287111-93-7)
- Ethyl 2-(3-fluoro-5-propoxyphenyl)-2-oxoacetate (CAS 1443350-25-1)
- 3,4-Dihydro-1h-spiro[naphthalene-2,2'-oxirane] (CAS 1407546-53-5)
- 4-(2,2,2-trifluoroethyl)morpholine-3-carboxylic acid hydrochloride (CAS 1803571-64-3)
- Ethyl (7R,8S)-8-amino-1,4-dioxaspiro[4.5]Decane-7-carboxylate 4-methylbenzenesulfonate (CAS 1004536-92-8)
- 2-Bromo-N-(4-chlorophenyl)acetamide (CAS 5343-64-6)
- (1E,4E)-4-Methyl-1-(trimethylsilyl)hexa-1,4-dien-3-one (CAS 81255-90-5)
- Pentoxyverine Impurity 12 (CAS CATO-C4X-227012)
- Fibrinogen-Binding Inhibitor Peptide (CAS 89105-94-2)
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