Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite CAS 128858-43-5

Purity 97%+In StockPharmaceutical Standards
CAS No.128858-43-5
Molecular FormulaC20H26Cl2NO2P
Molecular Weight414.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite CAS 128858-43-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite.

CATO supplies Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite (CAS 128858-43-5), a certified reference material (molecular formula C20H26Cl2NO2P, MW 414.31 g/mol) for analytical method development and quality control.

Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite (C20H26Cl2NO2P) contains a steroid core, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC20H26Cl2NO2P
Molecular Weight414.31 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentCl-containing
Nitrogen Atoms1

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