3-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine CAS 1288998-66-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1288998-66-2
Molecular FormulaC8H15N3O2
Molecular Weight185.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine CAS 1288998-66-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine.

3-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1288998-66-2) is a high-purity analytical reference standard with the molecular formula C8H15N3O2 and a molecular weight of 185.22 g/mol.

3-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine (C8H15N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H15N3O2
Molecular Weight185.22 g/mol
AppearanceWhite to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1990
Nitrogen Atoms3

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