6-fluoro-4-iodonicotinaldehyde CAS 1289017-52-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1289017-52-2
Molecular FormulaC6H3FINO
Molecular Weight251.00 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-fluoro-4-iodonicotinaldehyde CAS 1289017-52-2 chemical structure

Description

The occurrence of 6-fluoro-4-iodonicotinaldehyde is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-fluoro-4-iodonicotinaldehyde (CAS 1289017-52-2) is a high-purity analytical reference standard with the molecular formula C6H3FINO and a molecular weight of 251.00 g/mol.

The molecular framework of 6-fluoro-4-iodonicotinaldehyde (C6H3FINO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-fluoro-4-iodonicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H3FINO
Molecular Weight251.00 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF/I-containing
Nitrogen Atoms1

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