2-Fluoro-6-formylisonicotinonitrile CAS 1289158-76-4
| CAS No. | 1289158-76-4 |
| Molecular Formula | C7H3FN2O |
| Molecular Weight | 150.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Fluoro-6-formylisonicotinonitrile.
CATO supplies 2-Fluoro-6-formylisonicotinonitrile (CAS 1289158-76-4), a certified reference material (molecular formula C7H3FN2O, MW 150.11 g/mol) for analytical method development and quality control.
The molecular framework of 2-Fluoro-6-formylisonicotinonitrile (C7H3FN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3FN2O |
| Molecular Weight | 150.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 5-Fluoro-2-formylisonicotinonitrile (CAS 1211534-12-1)
- 6-Fluoro-4-formylpicolinonitrile (CAS 1288990-67-9)
- 3-Fluoro-4-formylpyridine-2-carbonitrile (CAS 1288994-60-4)
- 4-Fluoro-6-formylpicolinonitrile (CAS 1288999-70-1)
- 5-Fluoro-6-formylnicotinonitrile (CAS 1289010-78-1)
- 3-Fluoro-5-formylpicolinonitrile (CAS 952287-25-1)
- 2-(5-Fluoro-6-methylpyridin-2-yl)acetonitrile (CAS 1000555-87-2)
- 2-(6-Fluoro-5-methylpyridin-3-yl)acetonitrile (CAS 1000556-88-6)
Recommended Standards
- (3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-one (CAS 224957-07-7)
- 2,4-Diamino-3-Fluoro-4-Oxobutanoic Acid (CAS 72016-54-7)
- 3-(Dimethylphosphoryl)propanoic acid (CAS 63265-98-5)
- 5,5-dimethyl-1,3,2-dioxaphosphinan-2-ol (CAS 2553-49-3)
- 2-{[4-(2-fluorophenyl)piperazin-1-yl]methylidene}-2,3-dihydro-1H-indene-1,3-dione (CAS 1022101-16-1)
- 2-Chloro-1-(4-(4-chloro-3-(trifluoromethyl)phenyl)-5,6-dihydropyridin-1(2H)-yl)ethanone (CAS 1201225-04-8)
- 4-Amino-2-benzyl-5-chloropyridazin-3(2H)-one (CAS 37627-00-2)
- 5-Ethoxy-7,12-dimethyltetraphene (CAS 61441-20-1)
- (3-(5-Bromopyrimidin-2-yl)phenyl)methanol (CAS 1092568-90-5)
- (2-ethyl-4-methyl-1,3-oxazol-5-yl)methanol (CAS 137267-30-2)
- 2-Chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine (CAS 1805316-42-0)
- 5-Bromo-3-methoxypyrazole (CAS 1015779-81-3)
- N-Phenylquinolin-7-amine (CAS 688005-14-3)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com