1-(2-Chloro-6-fluorobenzyl)piperidin-4-amine hydrochloride CAS 1289385-36-9
| CAS No. | 1289385-36-9 |
| Molecular Formula | C12H16ClFN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(2-Chloro-6-fluorobenzyl)piperidin-4-amine hydrochloride (CAS 1289385-36-9), a certified reference material (molecular formula C12H16ClFN2HCl, MW 279.18 g/mol) for analytical method development and quality control.
1-(2-Chloro-6-fluorobenzyl)piperidin-4-amine hydrochloride (C12H16ClFN2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16ClFN2 HCl |
| Molecular Weight | 279.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- 3-[(2-Chloro-4-methylsulfonyl)phenoxy]benzoic acid (CAS 1000018-31-4)
- 6-Chloro-2-[2-(3-[(6-chloro-1-ethylbenz[c,d,]indole-2[1H]-ylidene)ethylidene]-2-phenyl-1-cyclopenten-1-yl)ethenyl]-1-ethylbenz[c,d]indolium tetrafluoroborate (CAS 100012-45-1)
- 3-Chloro-2-fluoro-5-iodobenzoic acid (CAS 1000162-09-3)
- (3-Chloro-2-fluoro-5-iodophenyl)methanol (CAS 1000162-10-6)
- 3-Chloro-2-fluoro-5-nitrobenzoic acid (CAS 1000162-34-4)
- 2-Chloro-N-(piperidin-4-yl)-6,7-dihydro-5H-cyclopenta-[d]pyrimidin-4-amine hydrochloride (CAS 1000207-51-1)
- 4-chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrimidine (CAS 1000303-40-1)
Recommended Standards
- 2-Bromo-3-chloro-6-ethoxyphenylboronic acid (CAS 1315476-02-8)
- Methyl 4-amino-3-phenylbutanoate (CAS 84872-79-7)
- 2-Chloro-3-methyl-4-nitrophenol (CAS 88062-27-5)
- 4-[4-(1H-Imidazol-1-yl)phenyl]-1,2,3-thiadiazole (CAS 303148-86-9)
- (R)-3-amino-2-(hydroxymethyl)propanoic acid hydrochloride (CAS 1956435-26-9)
- 5-Hydroxy-N,3-dimethyl-1H-pyrazole-1-carboxamide (CAS 85220-10-6)
- 2-(2-Phenyl-4-imidazolyl)acetonitrile (CAS 52353-66-9)
- (1-Acetoxy-2,2,5,5-tetramethyl-δ-3-pyrroline-3-methyl) Methanethiosulfonate (CAS 392718-69-3)
- rel-(1R,3S)-Ethyl 3-((Z)-2-chloro-2-(4-chlorophenyl)vinyl)-2,2-dimethylcyclopropanecarboxylate (CAS 78479-01-3)
- Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 90880-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com