2-(Piperazin-1-ylmethyl)benzonitrile hydrochloride CAS 1289388-18-6
| CAS No. | 1289388-18-6 |
| Molecular Formula | C12H15N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Piperazin-1-ylmethyl)benzonitrile hydrochloride (CAS 1289388-18-6) is a high-purity analytical reference standard with the molecular formula C12H15N3HCl and a molecular weight of 237.73 g/mol.
The molecular framework of 2-(Piperazin-1-ylmethyl)benzonitrile hydrochloride (C12H15N3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-(Piperazin-1-ylmethyl)benzonitrile hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15N3 HCl |
| Molecular Weight | 237.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- (3S,4S)-3-ethynyl-3-hydroxy-1,4-dimethyl-pyrrolidin-2-one (CAS 2561461-49-0)
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- 2,3-DIAMINOPROPIONOIC ACID (CAS 515-94-6)
- (1R,3S)-3-(2-(3-fluorophenyl)-2-oxoethyl)cyclohexane-1-carboxylic acid (CAS 735275-18-0)
- 2-Phenyl-3,4-dihydro-2H-1-benzopyran-4-amine (CAS 6517-15-3)
- 2-[(2-fluorophenyl)methyl]-1,3-thiazole-4-carboxylic acid (CAS 1216196-70-1)
- 3-(4-Ethylphenyl)propanamide (CAS 931998-40-2)
- 4-(3,3-Dimethyl-2-oxobutoxy)benzamide (CAS 924724-22-1)
- 3-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]-1-phenylurea (CAS 121829-01-4)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
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