Metamizole EP Impurity E Sodium Salt CAS 129-89-5
| CAS No. | 129-89-5 |
| Molecular Formula | C12H14N3O4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Metamizole EP Impurity E Sodium Salt is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 319.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Metamizole EP Impurity E Sodium Salt (CAS 129-89-5) is a certified pharmaceutical impurity reference standard with the molecular formula C12H14N3O4SNa and a molecular weight of 319.31 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N3O4S Na |
| Molecular Weight | 319.31 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Metamizole Standards
- Metamizole Monohydrate EP Impurity E (CAS 117-38-4(free base))
- Metamizole Impurity 15 (CAS 23197-23-1)
- Metamizole free (CAS 50567-35-6)
- Metamizole EP Impurity C (CAS 519-98-2)
- 【禁售不询】Metamizole EP Impurity D (CAS 58-15-1)
- Metamizole Sodium Monohydrate (CAS 5907-38-0)
- Metamizole Magnesium Salt (CAS 63372-86-1)
- Metamizole Impurity 5 (CAS 810-16-2)
Recommended Standards
- Fluconazole Impurity 53 (CAS CATO-C4X-101953)
- Mometasone Furoate EP Impurity O (CAS 24916-91-4)
- Dotinurad Impurity 256 (CAS CATO-C4X-2494256)
- 4-((3-Bromo-4-methoxybenzylidene)amino)-3-(2-methoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478257-42-0)
- 5-Ethynyl-3-methyl-1,2,4-thiadiazole (CAS 2098094-15-4)
- methyl 3-(3-methoxyphenyl)-3-(1H-1,2,3,4-tetrazol-1-yl)propanoate (CAS 2060031-50-5)
- 3-Methyl-N-(2-methylallyl)pentan-2-amine (CAS 1250008-23-1)
- 2-(1-Pyrrolidinyl)-2-[4-(trifluoromethyl)phenyl]ethylamine (CAS 885950-66-3)
- 2-(3-BRomo-4-methyl-benzenesulfinyl)-ethanol (CAS 1823954-25-1)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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