tert-Butyl (3-amino-1H-pyrazol-5-yl)carbamate CAS 1290181-43-9
| CAS No. | 1290181-43-9 |
| Molecular Formula | C8H14N4O2 |
| Molecular Weight | 198.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of tert-Butyl (3-amino-1H-pyrazol-5-yl)carbamate (C8H14N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
tert-Butyl (3-amino-1H-pyrazol-5-yl)carbamate (CAS 1290181-43-9) is a high-purity analytical reference standard with the molecular formula C8H14N4O2 and a molecular weight of 198.22 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14N4O2 |
| Molecular Weight | 198.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Recommended Standards
- tert-Butyl (5-methylisoxazol-4-yl)carbamate (CAS 1285517-13-6)
- 6-(Phenylamino)nicotinaldehyde (CAS 1292370-14-9)
- tert-Butyl (3-methylisoxazol-4-yl)carbamate (CAS 1285517-11-4)
- CCG 2046 (CAS 13017-69-1)
- 3-Nitro-4-(piperazin-1-yl)benzamide (CAS 335210-46-3)
- (1-(3-Fluoropyridin-2-yl)cyclobutyl)methanamine (CAS 1344145-48-7)
- N-(4-Fluorophenyl)(tert-butoxy)carbohydrazide (CAS 1075749-75-5)
- 1-Phenyl-3-(thiophen-3-yl)prop-2-en-1-one (CAS 106522-00-3)
- (4-Fluorophenyl) N-pyridin-2-ylcarbamate (CAS 469891-26-7)
- 1-Benzyl 8-tert-butyl 3-oxo-1,4,8-triazaspiro[5.5]undecane-1,8-dicarboxylate (CAS 1160247-12-0)
- 4-Piperidinol, 3-fluoro-4-(trifluoromethyl)-, (3R,4S)- (CAS 1932520-09-6)
- O,O-diethyl O-{6-(methoxymethyl)-2-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl} phosphothioate (CAS 261959-16-4)
- Methyl 3'-(((2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)methyl)-[1,1'-biphenyl]-4-carboxylate (CAS 887704-61-2)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
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