5-Chloro-3,4-dihydroisoquinolin-1(2H)-one CAS 129075-59-8
| CAS No. | 129075-59-8 |
| Molecular Formula | C9H8ClNO |
| Molecular Weight | 181.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chloro-3,4-dihydroisoquinolin-1(2H)-one (CAS 129075-59-8), a certified reference material (molecular formula C9H8ClNO, MW 181.62 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-3,4-dihydroisoquinolin-1(2H)-one (C9H8ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-3,4-dihydroisoquinolin-1(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8ClNO |
| Molecular Weight | 181.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1000340-14-6)
- 4-Chloro-7-methoxy-1H-indole (CAS 1000341-80-9)
- 4-Chloro-5-ethyl-7h-pyrrolo[2,3-d]pyrimidine (CAS 1004992-44-2)
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Recommended Standards
- 5-Amino-6-chloro-2,3-dihydro-1H-inden-1-one (CAS 1273611-33-8)
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- 2-(Chloromethyl)-3-methoxybenzonitrile (CAS 1261874-07-0)
- 4-Chloro-2-vinylbenzamide (CAS 131002-04-5)
- 6-(1H-1,2,4-triazol-1-yl)-N-(3-(trifluoromethyl)phenyl)nicotinamide (CAS 338418-95-4)
- 2-((4-(Tert-pentyl)cyclohexyl)amino)ethan-1-ol (CAS 1039974-37-2)
- 7-Methoxy-4-methylquinazolin-2(1H)-one (CAS 37528-39-5)
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- 3-(3-Methoxy-4-nitrophenyl)-9-methyl-3,9-diazaspiro[5.5]undecane (CAS 1854943-73-9)
- 4-prop-2-ynylpiperazin-2-one (CAS 1219606-29-7)
- 3-Isobutoxypyrazine-2-carboxylic acid (CAS 1341898-11-0)
- n-(3-Hydroxyphenyl)-3-iodobenzamide (CAS 1040025-91-9)
- (S)-1-(2,4-difluorophenyl)-2-methylpropan-1-amine (CAS 1213059-66-5)
- Acetyl decapeptide-3 (CAS 935288-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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