Methyl 5-cyclopropyl-4-iodo-1H-pyrazole-3-carboxylate CAS 1291275-81-4
| CAS No. | 1291275-81-4 |
| Molecular Formula | C8H9IN2O2 |
| Molecular Weight | 292.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 5-cyclopropyl-4-iodo-1H-pyrazole-3-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 5-cyclopropyl-4-iodo-1H-pyrazole-3-carboxylate (CAS 1291275-81-4) is a high-purity analytical reference standard with the molecular formula C8H9IN2O2 and a molecular weight of 292.07 g/mol.
The molecular framework of Methyl 5-cyclopropyl-4-iodo-1H-pyrazole-3-carboxylate (C8H9IN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9IN2O2 |
| Molecular Weight | 292.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 2-(3-Cyclopropyl-4-iodo-1H-pyrazol-1-yl)acetic acid (CAS 1354703-67-5)
- N-(5-Cyclopropyl-1,3,4-thiadiazol-2-yl)-2-(methylthio)nicotinamide (CAS 775309-33-6)
- 1-Cyclopropyl-3-(thiophen-2-yl)-1-(2-(thiophen-2-yl)ethyl)urea (CAS 1396800-44-4)
- N-Cyclopropyl-2-((4-methoxybenzo[d]thiazol-2-yl)(methyl)amino)acetamide (CAS 1351662-29-7)
- N-[5-cyclopropyl-3-(3-fluorophenyl)-1H-pyrazol-4-yl]-2-methylpropanamide (CAS 1190260-34-4)
- 2-[3-(Cyclopropyl-methyl-amino)-pyrrolidin-1-yl]-ethanol (CAS 1353985-89-3)
- N-Cyclopropyl-3-(1H-indazol-5-yl)-4-methylbenzamide (CAS 651780-47-1)
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Recommended Standards
- Methyl 3,4-diamino-5-iodobenzoate (CAS 1258940-57-6)
- ETHYL 5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE (CAS 1346569-65-0)
- 5-Iodo-2-methoxy-4-methylbenzoic acid (CAS 1241674-09-8)
- Methyl 4-hydroxy-3-iodo-5-methylbenzoate (CAS 1194545-63-5)
- (R)-2-((o-Tolyloxy)methyl)morpholine hydrochloride (CAS 56324-45-9)
- 2-Bromo-5-methylthiazole-4-carbaldehyde (CAS 1379318-90-7)
- 2-(3-cyclopropyl-1-methyl-1H-1,2,4-triazol-5-yl)acetic acid (CAS 1343789-51-4)
- Boc-Lys(Z)-OH (CAS 2389-45-9)
- 1-Phenylhex-5-en-1-one (CAS 22524-25-0)
- 6-Phenyl-1-indanone (CAS 170497-64-0)
- 3-[5-(furan-2-yl)-1,3-oxazol-2-yl]propanoic acid (CAS 1016674-88-6)
- N-Ethyl-N,N-dimethyl-2-phenylethanaminium Bis((trifluoromethyl)sulfonyl)amide (CAS 1804970-28-2)
- Butyl 1-oxoisochromane-3-carboxylate (CAS 499209-44-8)
- Peptide 74 (H-8545.0500) (CAS 132116-39-3)
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