8-(Azepan-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol CAS 1291486-98-0
| CAS No. | 1291486-98-0 |
| Molecular Formula | C12H16N4O3S |
| Molecular Weight | 296.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-(Azepan-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol.
CATO supplies 8-(Azepan-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (CAS 1291486-98-0), a certified reference material (molecular formula C12H16N4O3S, MW 296.35 g/mol) for analytical method development and quality control.
The molecular framework of 8-(Azepan-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (C12H16N4O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16N4O3S |
| Molecular Weight | 296.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Azepan Standards
- 6-(Azepan-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (CAS 1291855-40-7)
- 1-(Azepan-1-yl)-2-(4-bromophenyl)ethan-1-one (CAS 349429-30-7)
- 5-(Azepan-1-yl)-7-chloro-4-nitrobenzo[c][1,2,5]oxadiazole (CAS 310451-77-5)
- 3-(Azepan-1-ylsulfonyl)-4-methylbenzoic acid (CAS 418790-58-6)
- 5-(Azepan-1-ylsulfonyl)-2-methylbenzoic acid (CAS 637320-93-5)
- (6-(Azepan-1-yl)-5-methylpyridin-3-yl)(phenyl)methanone (CAS 1355219-52-1)
- 2-[(2E)-Azepan-2-ylidene]-2-(2-fluorobenzenesulfonyl)acetonitrile (CAS 1327197-46-5)
- 1-(2-(Azepan-1-yl)-2-oxoethyl)-2-methyl-1H-indole-3-carbaldehyde (CAS 626205-51-4)
Recommended Standards
- N-(3-(2-Methylthiazol-4-yl)phenyl)pyrimidine-2-carboxamide (CAS 1251706-34-9)
- 6-((4-Methylpiperidin-1-yl)sulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (CAS 1291834-57-5)
- 1-[5-(2-Oxopyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]piperidine-4-carboxylic acid (CAS 1243100-34-6)
- 1-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-amine (CAS 1176583-70-2)
- 4-Fluoro-5-methoxy-2-nitrobenzamide (CAS 864293-51-6)
- 1-(4-(((1-Ethyl-5-methyl-1H-pyrazol-4-yl)methyl)amino)phenyl)butan-1-one (CAS 1091670-51-7)
- 5-Chloro-2-nitropyridin-4-ol (CAS 1807250-01-6)
- 2-Chloro-N-cyclopropyl-6-methyl-4-pyrimidinamine (CAS 1250038-98-2)
- 1-Methyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one (CAS 1437385-29-9)
- Ethyl 3-amino-1-benzyl-4-cyano-1H-pyrrole-2-carboxylate (CAS 731825-89-1)
- (2S,3R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4,4,4-trifluoro-3-methylbutanoic acid (CAS 1414349-24-8)
- N-[1-(4-Allyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-ethyl]-benzamide (CAS 792941-55-0)
- Brivaracetam Impurity 13 (CAS 2252417-17-5)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
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