3-Amino-4-(2,4-dichlorophenyl)-1-(3,4-dimethoxybenzyl)azetidin-2-one CAS 1291487-95-0
| CAS No. | 1291487-95-0 |
| Molecular Formula | C18H18Cl2N2O3 |
| Molecular Weight | 381.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 381.25 g/mol gives 3-Amino-4-(2,4-dichlorophenyl)-1-(3,4-dimethoxybenzyl)azetidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Amino-4-(2,4-dichlorophenyl)-1-(3,4-dimethoxybenzyl)azetidin-2-one (CAS 1291487-95-0) is a high-purity analytical reference standard with the molecular formula C18H18Cl2N2O3 and a molecular weight of 381.25 g/mol.
The molecular framework of 3-Amino-4-(2,4-dichlorophenyl)-1-(3,4-dimethoxybenzyl)azetidin-2-one (C18H18Cl2N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Amino-4-(2,4-dichlorophenyl)-1-(3,4-dimethoxybenzyl)azetidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18Cl2N2O3 |
| Molecular Weight | 381.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile (CAS 915019-52-2)
- 2-Amino-6-(4-bromophenyl)-4-phenyl-5H-pyrrolo[3,4-d]pyrimidin-7(6H)-one (CAS 76628-82-5)
- Ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 906088-96-8)
- Ethyl 3-((2-amino-5-chlorophenyl)thio)-5-chloro-1H-indole-2-carboxylate (CAS 206256-25-9)
- (S)-1-(Amino(phenyl)methyl)naphthalen-2-ol (2R,3R)-2,3-dihydroxysuccinate (CAS 219897-70-8)
- (S)-2-Amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)amino)butanoic acid (CAS 111770-79-7)
- 4-Amino-6-(naphthalen-1-yl)-3-phenyl-3,7-dihydropyrimido[5,4-d]pyrimidine-2,8-dione (CAS 1119392-02-7)
- 2-Amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)amino)butanoic Acid (CAS 129828-73-5)
Recommended Standards
- tert-Butyl 3-(iodomethyl)-2-oxa-8-azaspiro[4.5]decane-8-carboxylate (CAS 1250998-93-6)
- Bodipy Isothiocyanate (CAS 1349031-04-4)
- 1142205-15-9 9334AC C18H18Cl2N2O3 [(2-{[2-(2,4-Dichlorophenyl)ethyl]amino}-2-oxoethyl)(phenyl)amino]acetic acid (CAS 1142205-15-9)
- tert-butyl 2-(iodomethyl)-1-oxa-8-azaspiro[4.5]decane-8-carboxylate (CAS 1373028-07-9)
- 5-(Difluoromethyl)-3-iodo-4-methylpyridin-2-amine (CAS 1805961-79-8)
- PD 089828 (CAS 179343-17-0)
- 2-Bromo-N,N-dimethyl-4-(trifluoromethyl)aniline (CAS 1369856-62-1)
- Octan-2-yl acrylate (CAS 42928-85-8)
- 5-Chloro-8-fluoroquinoline (CAS 500579-51-1)
- 2-Bromo-4-chlorobenzenethiol (CAS 54404-01-2)
- 2-Phenyl-1-(5-(thiomorpholine-4-carbonyl)-1H-pyrrol-3-yl)ethan-1-one (CAS 477870-61-4)
- N,N'-Bis(2,4-difluorophenyl)-2-[(1E)-(methoxyimino)methyl]propanediamide (CAS 339096-54-7)
- 2-(2,5-Dichlorophenyl)pyrrole (CAS 99113-94-7)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com