3-Amino-4-(5-bromothiophen-2-yl)-1-(3,4-dimethoxybenzyl)azetidin-2-one CAS 1291489-10-5
| CAS No. | 1291489-10-5 |
| Molecular Formula | C16H17BrN2O3S |
| Molecular Weight | 397.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-4-(5-bromothiophen-2-yl)-1-(3,4-dimethoxybenzyl)azetidin-2-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-4-(5-bromothiophen-2-yl)-1-(3,4-dimethoxybenzyl)azetidin-2-one (CAS 1291489-10-5) is a high-purity analytical reference standard with the molecular formula C16H17BrN2O3S and a molecular weight of 397.29 g/mol.
The molecular framework of 3-Amino-4-(5-bromothiophen-2-yl)-1-(3,4-dimethoxybenzyl)azetidin-2-one (C16H17BrN2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-4-(5-bromothiophen-2-yl)-1-(3,4-dimethoxybenzyl)azetidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H17BrN2O3S |
| Molecular Weight | 397.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 1138445-64-3 2-Bromo-N-{4-[(ethylanilino)sulfonyl]-phenyl}acetamide 9146AC C16H17BrN2O3S (CAS 1138445-64-3)
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- N-(4-{[Benzyl(methyl)amino]sulfonyl}phenyl)-2-bromoacetamide (CAS 1138445-63-2)
- 3-(1-(3-(4-Bromophenyl)propanoyl)pyrrolidin-3-yl)thiazolidine-2,4-dione (CAS 1795481-46-7)
- 1,1-Dichloro-2,2,3,3,3-pentafluoropropane DISCONTINUED (CAS 422-56-0)
- 4-[(2-Phenoxyethyl)amino]butanoic acid (CAS 1016531-72-8)
- 2,2-Dibromo-1-(3,5-dimethoxyphenyl)ethan-1-one (CAS 188199-76-0)
- 1-(3-Methoxyphenyl)-4,4-dimethyl-1,4-dihydropyrimidine-2-thiol (CAS 259683-70-0)
- 3-Fluoro-4-methoxyphenethyl acetate (CAS 1443351-05-0)
- Ethyl 4-(tert-butyl)-2-chlorothiazole-5-carboxylate (CAS 72850-77-2)
- N-Methoxy-N-methyl-4-oxocyclohexanecarboxamide (CAS 1203856-37-4)
- 6-[(E)-(3-Methoxyphenyl)methylidene]-6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-5-one (CAS 112547-47-4)
- 2-Chloro-4-Methylbenzoyl chloride (CAS 21900-53-8)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
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