4-((Tetrahydrofuran-2-yl)methoxy)benzo[b]thiophene-6-carboxylic acid CAS 1291491-13-8
| CAS No. | 1291491-13-8 |
| Molecular Formula | C14H14O4S |
| Molecular Weight | 278.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-((Tetrahydrofuran-2-yl)methoxy)benzo[b]thiophene-6-carboxylic acid (C14H14O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-((Tetrahydrofuran-2-yl)methoxy)benzo[b]thiophene-6-carboxylic acid (CAS 1291491-13-8), molecular formula C14H14O4S and molecular weight 278.32 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-((Tetrahydrofuran-2-yl)methoxy)benzo[b]thiophene-6-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14O4S |
| Molecular Weight | 278.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Sulfur Atoms | 1 |
Related Tetrahydrofuran Standards
- 1-((Tetrahydrofuran-2-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1233526-35-6)
- 1-((Tetrahydrofuran-3-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1605294-11-8)
- 1-((Tetrahydrofuran-3-yl)methyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2246449-36-3)
- 1-Oxo-2-((tetrahydrofuran-2-yl)methyl)-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid (CAS 1212119-77-1)
- 4-Oxo-5-((tetrahydrofuran-2-yl)methyl)-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine-2-carboxylic acid (CAS 1713639-49-6)
- Methyl 4-((tetrahydrofuran-2-yl)methoxy)benzofuran-6-carboxylate (CAS 1291489-18-3)
- 2-Methyl-4-((tetrahydrofuran-2-yl)methoxy)benzofuran-6-carboxylic acid (CAS 1291493-44-1)
- 2-(Tetrahydrofuran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 2223003-22-1)
Recommended Standards
- 5-((Benzylthio)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 128889-73-6)
- 1-(Benzyloxy)-4-(3-fluorophenyl)benzene (CAS 1352318-28-5)
- 3-[(2-methylphenyl)methanesulfinylmethyl]furan-2-carboxylic acid (CAS 1274622-84-2)
- 1-(Benzyloxy)-3-(3-fluorophenyl)benzene (CAS 1355247-13-0)
- 1-(4,6-Dimethyl-1H-pyrazolo[3,4-b]pyridin-3-yl)thiourea (CAS 866017-67-6)
- 3-(Difluoromethoxy)-2-iodobenzoic acid (CAS 2383082-26-4)
- 2-(Difluoromethyl)-5-methoxy-4-(trifluoromethoxy)pyridine-3-acetonitrile (CAS 1806161-08-9)
- N-(2,4-Dimethylphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide (CAS 1775453-84-3)
- 4-Amino-N-(4-chlorophenyl)benzenesulfonamide (CAS 16803-92-2)
- 5-(3-Nitrophenyl)-1H-1,2,4-triazole-3-thiol (CAS 6219-47-2)
- 4-Cyclopropoxy-5-methylpicolinamide (CAS 1243464-79-0)
- N2,N2-diethyl-5-nitropyrimidine-2,4-diamine (CAS 856973-04-1)
- 4-Butoxy-N-(1,3,4-thiadiazol-2-yl)benzamide (CAS 866010-65-3)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
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