2-(2H-chromen-3-yl)thiazole-4-carboxylic acid CAS 1291493-48-5
| CAS No. | 1291493-48-5 |
| Molecular Formula | C13H9NO3S |
| Molecular Weight | 259.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2H-chromen-3-yl)thiazole-4-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(2H-chromen-3-yl)thiazole-4-carboxylic acid (CAS 1291493-48-5), a certified reference material (molecular formula C13H9NO3S, MW 259.28 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2H-chromen-3-yl)thiazole-4-carboxylic acid (C13H9NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H9NO3S |
| Molecular Weight | 259.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related H Standards
- 2-(3-(2H-Chromen-3-yl)-1,2,4-oxadiazol-5-yl)acetic acid (CAS 1269531-42-1)
- 2-(2H-Chromen-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1031747-53-1)
- 3-(2H-Chromen-3-yl)-N-cyclopentylacrylamide (CAS 887347-58-2)
- 1-(3-(2H-Chromen-3-yl)-1,2,4-oxadiazol-5-yl)-2-methylpropan-1-amine (CAS 1269531-05-6)
- 2-(2-(2H-chromen-3-yl)thiazol-4-yl)acetic acid (CAS 1291490-26-0)
- 3-(2H-Chromen-3-yl)-1,2,4-oxadiazole-5-carboxylic acid (CAS 1269534-55-5)
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Recommended Standards
- 2-Amino-1-(4-fluoro-2-methoxyphenyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 1290710-52-9)
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- (2E)-1-(3-Nitrophenyl)-3-(thiophen-2-yl)prop-2-en-1-one (CAS 1287790-76-4)
- 1-(1-(Methylsulfonyl)pyrrolidin-3-yl)-1H-pyrazole-4-carboxylic acid (CAS 1316225-68-9)
- 1-[4-(2,2-difluoroethoxy)phenyl]propan-1-amine,HCl (CAS 1431963-43-7)
- 1-(2-Cyclopropyl-1,3-thiazol-4-yl)ethan-1-ol (CAS 1339731-23-5)
- (4-(Methylthio)phenyl)(pyridin-2-yl)methanone (CAS 95898-77-4)
- Oxymesterone (CAS 145-12-0)
- 2,3-Dichloro-5-fluoroaniline (CAS 1699950-48-5)
- 2,5-Difluoro-3-methylbenzenesulfonyl chloride (CAS 1803825-42-4)
- (9H-fluoren-9-yl)triphenylphosphonium bromide (CAS 7253-07-8)
- (3s)-3-amino-3-(2-chlorophenyl)propanoic acid (S)-beta-(2-Chlorophenyl)alanine (s)-3-(2-chlorophenyl)-beta-alanine (s)-3-amino-3-(2-chloro-phenyl)-propanoic acid (s)-3-amino-3-(2-chloro-phenyl)-propionic acid (s)-3-amino-3-(2-chlorophenyl)propanoic acid (s)-3-amino-3-(2-chlorophenyl)propionic acid 763922-37-8 benzenepropanoic acid, beta-amino-2-chloro-, (betas)- h-beta-phe(2-cl)-oh h-d-phg(2-cl)-(c*ch2)oh s-3-amino-3-(2-chloro-phenyl)-propionic acid (CAS 763922-37-8)
- 2-(Chloromethyl)-5-(pyrrolidin-1-yl)-1,3,4-oxadiazole (CAS 1700444-24-1)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
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