5-Chloro-3-(2,4-dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazoline CAS 129177-22-6
| CAS No. | 129177-22-6 |
| Molecular Formula | C15H7Cl3N4 |
| Molecular Weight | 349.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-3-(2,4-dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-3-(2,4-dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 129177-22-6), a certified reference material (molecular formula C15H7Cl3N4, MW 349.60 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-3-(2,4-dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazoline (C15H7Cl3N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H7Cl3N4 |
| Molecular Weight | 349.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
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- 4-Amino-N-ethyl-N-(naphthalen-1-yl)benzamide (CAS 6361-29-1)
- (4-(4-(Trifluoromethyl)phenoxy)phenyl)boronic acid (CAS 1415824-94-0)
- 4-[bis[4-(diethylamino)phenyl]methyl]-1,3-Benzenedisulfonic acid disodium salt (CAS 133978-89-9)
- 2-(2-((tert-Butoxycarbonyl)amino)benzo[d]thiazol-6-yl)acetic acid (CAS 1440526-62-4)
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- 1-Isopropyldibenzo[b,d]thiophene (CAS 376364-06-6)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
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