5-Amino-6-bromonicotinic acid CAS 1292765-17-3
| CAS No. | 1292765-17-3 |
| Molecular Formula | C6H5BrN2O2 |
| Molecular Weight | 217.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-6-bromonicotinic acid.
CATO supplies 5-Amino-6-bromonicotinic acid (CAS 1292765-17-3), a certified reference material (molecular formula C6H5BrN2O2, MW 217.02 g/mol) for analytical method development and quality control.
The molecular framework of 5-Amino-6-bromonicotinic acid (C6H5BrN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5BrN2O2 |
| Molecular Weight | 217.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 1000339-23-0 2-AMINO-5-BROMO-4-PYRIDINECARBOXYLIC ACID 2-AMINO-5-BROMOISONICOTINIC ACID 2-AMINO-5-BROMOPYRIDINE-4-CARBOXYLIC ACID BC003478 (CAS 1000339-23-0)
- 6-Amino-3-bromopicolinic acid (CAS 1033201-61-4)
- 3-Amino-6-bromopyridine-2-carboxylic Acid (CAS 1052708-46-9)
- 4-Amino-2-bromonicotinic acid (CAS 1060809-71-3)
- 4-Amino-6-bromopicolinic acid (CAS 1060811-27-9)
- 2-Amino-6-bromoisonicotinic acid (CAS 1060811-29-1)
- 4-Amino-6-bromonicotinic acid (CAS 1060811-30-4)
- 2-Amino-6-bromonicotinic acid (CAS 1196157-51-3)
Recommended Standards
- (4-Bromopyridin-2-yl)carbamic acid (CAS 1279205-05-8)
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- 6-Amino-4-bromopicolinic acid (CAS 1353101-32-2)
- 4,7-Dimethylbenzofuran-5-amine (CAS 214682-84-5)
- 2-(Chloromethyl)-5-(2,6-dichlorophenyl)-1,3,4-oxadiazole (CAS 1016503-65-3)
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- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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