7,8-Dimethoxy-2-methylquinoline CAS 129376-54-1
| CAS No. | 129376-54-1 |
| Molecular Formula | C12H13NO2 |
| Molecular Weight | 203.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7,8-Dimethoxy-2-methylquinoline (C12H13NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
7,8-Dimethoxy-2-methylquinoline (CAS 129376-54-1) is a high-purity analytical reference standard with the molecular formula C12H13NO2 and a molecular weight of 203.24 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13NO2 |
| Molecular Weight | 203.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 1 |
Related Dimethoxy Standards
- 5,6-Dimethoxy-2,3-dihydro-1H-indene-1-carbonitrile (CAS 130489-93-9)
- 6,7-Dimethoxy-4-methylisoquinoline (CAS 18029-55-5)
- 1,4-Dimethoxy-2-naphthylamine (CAS 50885-06-8)
- 2,4-Dimethoxy-7-methylquinoline (CAS 406205-07-0)
- 5,6-Dimethoxy-1-methylisoquinoline (CAS 30836-91-0)
- 5,6-Dimethoxy-2-methylquinoline (CAS 882159-12-8)
- 5,8-Dimethoxy-2-methylquinoline (CAS 58868-31-8)
- 6,7-Dimethoxy-1-methylisoquinoline hydrochloride (CAS 4722-12-7)
Recommended Standards
- (S)-2-amino-N-(3-cyanobenzyl)propanamide (CAS 1292746-27-0)
- Methyl 4-(2-cyanopropan-2-yl)benzoate (CAS 129488-73-9)
- 5-(4-Ethoxyphenyl)-1H-pyrazol-3-amine (CAS 129117-13-1)
- 1-Acetyl-2-Methyl-2,3-Dihydroquinolin-4(1H)-One (CAS 128649-34-3)
- 1-(2-(Trifluoromethyl)pyridin-4-yl)cyclopropane-1-carboxylic acid (CAS 1427013-07-7)
- 2-(8-(Tert-butoxycarbonyl)-1-(cyclohexylmethyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-3-yl)acetic acid (CAS 180386-37-2)
- (2,4-Dimethoxyphenyl)(quinolin-4-yl)methanone 1706436-30-7 (CAS 1706436-30-7)
- potassium trifluoro(3-(hydroxymethyl)phenyl)borate (CAS 1015082-77-5)
- 1-[4-(3,4-Dimethoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-amine (CAS 1171834-04-0)
- 4-Methoxy-3-methylbenzimidamide (CAS 126007-97-4)
- 1-Chloro-2-fluoro-4-isopropoxybenzene (CAS 1369813-97-7)
- 2-(3-Bromo-4-fluorophenyl)-1-(4-methoxy-3-methylphenyl)ethan-1-one (CAS 1209495-16-8)
- 1-(3-FLuoro-5-nitrobenzoyl)piperidine (CAS 1498256-25-9)
- Semaglutide impurity 261 (CAS CATO-C4X-2226261)
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