5,7-Difluoroquinoline-3-carboxylic acid CAS 1296950-83-8
| CAS No. | 1296950-83-8 |
| Molecular Formula | C10H5F2NO2 |
| Molecular Weight | 209.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 209.15 g/mol gives 5,7-Difluoroquinoline-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5,7-Difluoroquinoline-3-carboxylic acid (CAS 1296950-83-8) is a high-purity analytical reference standard with the molecular formula C10H5F2NO2 and a molecular weight of 209.15 g/mol.
The molecular framework of 5,7-Difluoroquinoline-3-carboxylic acid (C10H5F2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5,7-Difluoroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5F2NO2 |
| Molecular Weight | 209.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroquinoline Standards
- 5,8-Difluoroquinoline-3-carboxylic acid (CAS 1296951-06-8)
- 5,6-Difluoroquinoline-2-carboxylic acid (CAS 1330751-48-8)
- 5,7-Difluoroquinoline-6-carboxylic acid (CAS 1398504-28-3)
- 3,7-Difluoroquinoline-4-carboxylic acid (CAS 834884-20-7)
- 7,8-Difluoroquinoline-3-carboxylic acid (CAS 318685-41-5)
- 5,8-Difluoroquinoline-4(1H)-thione (CAS 1065088-62-1)
- 5,7-Difluoroquinoline-6-carbaldehyde (CAS 1185767-02-5)
- 5,8-Difluoroquinoline-2-carbaldehyde (CAS 1266835-21-5)
Recommended Standards
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- 1-(2,6-Difluorophenyl)-1H-pyrrole-2,5-dione (CAS 134366-03-3)
- Methyl 4-chloro-2,2-dimethylpent-4-enoate (CAS 86799-85-1)
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- 1-(Thiazol-2-yl)urea (CAS 35107-91-6)
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