3-Acetylimidazo[1,2-a]pyridin-2(3H)-one CAS 129820-74-2
| CAS No. | 129820-74-2 |
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Acetylimidazo[1,2-a]pyridin-2(3H)-one.
CATO supplies 3-Acetylimidazo[1,2-a]pyridin-2(3H)-one (CAS 129820-74-2), a certified reference material (molecular formula C9H8N2O2, MW 176.17 g/mol) for analytical method development and quality control.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 3-Acetylimidazo[1,2-a]pyridin-2(3H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 176.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Acetylimidazo[1,2-a]pyridin-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 2 |
Related Acetylimidazo Standards
Recommended Standards
- Cyano(pyridin-3-yl)methyl acetate (CAS 129803-30-1)
- Methyl pyrrolo[1,2-a]pyrazine-3-carboxylate (CAS 1300034-27-8)
- 6-Ethynyl-4-methoxybenzo[d][1,3]dioxole (CAS 1291486-34-4)
- 2-Formylcinnamic acid (CAS 130036-17-8)
- 4-Bromo-N,2-dimethyl-2,3-dihydro-1H-inden-1-amine (CAS 1502861-61-1)
- Nipradolol (CAS 81486-22-8)
- 1-(7-(2,3-Dichlorophenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one (CAS 867042-67-9)
- Olaparib impurity 140 (CAS CATO-C4X-1135140)
- 2-(1,3-dihydro-2-benzofuran-1-yl)acetic acid (CAS 170856-90-3)
- 4-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine (CAS 499795-77-6)
- 5-Nitro-3-(5-(trifluoromethyl)pyridin-3-yl)-1H-indazole (CAS 1356088-06-6)
- 2-(2-Acetylbenzo[d]oxazol-6-yl)acetonitrile (CAS 1804214-04-7)
- 4-(Trifluoromethoxy)-2,3-dihydro-1H-isoindole (CAS 1895724-99-8)
- Endo-[Glu]31-Liraglutide (CAS CATO-C4X-199234)
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