Quinine Hydrochloride CAS 130-89-2
| CAS No. | 130-89-2 |
| Molecular Formula | C20H24N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Quinine Hydrochloride (CAS 130-89-2), molecular formula C20H24N2O2HCl and molecular weight 360.88 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Quinine Hydrochloride (C20H24N2O2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 360.88 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O2 HCl |
| Molecular Weight | 360.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Quinine Standards
- Quinine Sulfate Impurity 5 (CAS 101655-92-9)
- Quinine Impurity 1 (CAS 1092116-26-1)
- Quinine N-Oxide (CAS 109906-48-1)
- Quinine (CAS 130-95-0)
- Quinine Sulfate (500 mg) (CAS 207671-44-1)
- Quinine sulfate Impurity 6 (CAS 485-71-2)
- Quinine Sulfate - Impurity C (Sulfate Salt) (CAS 49722-46-5)
- Quinine Sulfate EP Impurity C (CAS 522-66-7)
Recommended Standards
- 8-Bromo-6-fluorochroman (CAS 746638-33-5)
- 3-bromo-1-(4-methylphenyl)-1H-pyrazole-5-carboxylic acid (CAS 1247686-99-2)
- 2-Amino-4-(4-methoxyphenyl)-7,7-dimethyl-1-(3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile (CAS 311318-23-7)
- N-(2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)propan-2-amine (CAS 2096340-07-5)
- 4-(2-Hydroxyethyl)-5-methyl-2-phenyl-1-((2,4,6-trichlorophenyl)sulfonyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 866039-78-3)
- 1-(3,4,5-Trimethoxyphenyl)propan-1-ol (CAS 29652-81-1)
- N-(4-iodophenyl)ethanesulfonamide (CAS 61738-45-2)
- 3-(1-Ethyl-1H-pyrazol-4-yl)-isoxazole-5-carboxylic acid (CAS 957487-34-2)
- 1-[(4-methoxybenzene)sulfonyl]piperidin-4-one (CAS 196085-08-2)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
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