(5R)-rel-5-(Fluoromethyl)pyrrolidine-2-carboxylic acid CAS 1301204-77-2
| CAS No. | 1301204-77-2 |
| Molecular Formula | C6H10FNO2 |
| Molecular Weight | 147.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 147.15 g/mol gives (5R)-rel-5-(Fluoromethyl)pyrrolidine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(5R)-rel-5-(Fluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1301204-77-2), molecular formula C6H10FNO2 and molecular weight 147.15 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (5R)-rel-5-(Fluoromethyl)pyrrolidine-2-carboxylic acid (C6H10FNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 147.15 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (5R)-rel-5-(Fluoromethyl)pyrrolidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10FNO2 |
| Molecular Weight | 147.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Methyl (2S,4S)-4-fluoropyrrolidine-2-carboxylate (CAS 126111-12-4)
- rel-(2S,5R)-5-Fluoropiperidine-2-carboxylic acid (CAS 1301204-87-4)
- Methyl (2S,4R)-4-fluoropyrrolidine-2-carboxylate (CAS 126111-11-3)
- rel-(2R,5R)-5-Fluoropiperidine-2-carboxylic acid (CAS 1301204-97-6)
- Methyl 7-fluoro-1H-indazole-3-carboxylate (CAS 932041-13-9)
- 3-Bromo-2-fluoropyridine (CAS 36178-05-9)
- 1-(Prop-2-yn-1-yl)-1H-indole (CAS 19017-00-6)
- 5-Chloro-2-phenoxypyridine (CAS 28373-51-5)
- N1-(4-Fluorophenyl)-N2-(thiophen-2-ylmethyl)oxalamide (CAS 898357-44-3)
- N-Phenylquinoline-4-carboxamide (CAS 92119-01-2)
- 4'-Demethyl Homoharringtonine-13C,d3 (CAS 1217669-36-7)
- N-((2-Chlorothiazol-5-yl)methyl)cyclopropanamine hydrochloride (CAS 1353964-90-5)
- 4-Isopropoxy-2-methylaniline (CAS 676366-02-2)
- Tetrapeptide-30/Tegopep (CAS 1036207-61-0)
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