2-Amino-6-bromoquinazolin-4-ol CAS 130148-53-7
| CAS No. | 130148-53-7 |
| Molecular Formula | C8H6BrN3O |
| Molecular Weight | 240.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Amino-6-bromoquinazolin-4-ol (CAS 130148-53-7) is a high-purity analytical reference standard with the molecular formula C8H6BrN3O and a molecular weight of 240.06 g/mol.
2-Amino-6-bromoquinazolin-4-ol (C8H6BrN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-6-bromoquinazolin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN3O |
| Molecular Weight | 240.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 3-Amino-6-bromoquinoxalin-2(1H)-one (CAS 1083181-48-9)
- 4-Amino-6-bromoquinazolin-2(1H)-one (CAS 1093201-96-7)
- 3-Amino-7-bromoquinoxalin-2-ol (CAS 1201845-05-7)
- 2-Amino-5-bromoquinazolin-4(1H)-one (CAS 937668-63-8)
- 3-Amino-6-bromobenzofuran-2-carbaldehyde (CAS 1823898-96-9)
- 2-Amino-6-bromo-4H-chromen-4-one (CAS 81563-94-2)
- 2-Amino-7-bromo-4H-chromen-4-one (CAS 2228007-01-8)
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Recommended Standards
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- (Z)-5-bromo-3-hydrazonoindolin-2-one (CAS 1268694-53-6)
- (5-Iodothiophen-2-yl)methanol (CAS 13781-27-6)
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- Benzenesulfonic Impurity 3 (CAS 1352414-81-3)
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