4-(4-Bromo-2-fluoro-5-methylphenyl)-thiosemicarbazide CAS 1303993-93-2
| CAS No. | 1303993-93-2 |
| Molecular Formula | C8H9BrFN3S |
| Molecular Weight | 278.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Bromo-2-fluoro-5-methylphenyl)-thiosemicarbazide.
CATO supplies 4-(4-Bromo-2-fluoro-5-methylphenyl)-thiosemicarbazide (CAS 1303993-93-2), a certified reference material (molecular formula C8H9BrFN3S, MW 278.14 g/mol) for analytical method development and quality control.
The molecular framework of 4-(4-Bromo-2-fluoro-5-methylphenyl)-thiosemicarbazide (C8H9BrFN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9BrFN3S |
| Molecular Weight | 278.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Bromo Standards
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- 4-(4-Bromo-5-fluoro-2-methylphenyl)-thiosemicarbazide (CAS 1303993-92-1)
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Recommended Standards
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- (R)-1-Boc-5-(bromomethyl)pyrrolidin-2-one (CAS 128811-38-1)
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- 4-Iodo-5-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-amine (CAS 1354704-16-7)
- Potassium O-benzyl carbonodithioate (CAS 2720-79-8)
- (1S,5R)-6,6-difluoro-3-azabicyclo[3.2.0]Heptane (CAS 1330764-78-7)
- 1-(6-Amino-5-fluoro-2-methylpyridin-3-yl)-2-bromoethan-1-one (CAS 2920209-92-1)
- 6-Chloroimidazo[1,2-b]pyridazine-3-carbaldehyde (CAS 154578-26-4)
- Dimethyl 2-bromo-5-Fluoroterephthalic acid (CAS 1245807-10-6)
- 6-(Aminomethyl)-3-(difluoromethyl)-4-nitropyridin-2-amine (CAS 1804717-20-1)
- 7-Bromo Darifenacin (CAS 1391080-43-5)
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