3-(2-Fluoro-4-nitrophenoxy)piperidine CAS 1304078-01-0
| CAS No. | 1304078-01-0 |
| Molecular Formula | C11H13FN2O3 |
| Molecular Weight | 240.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(2-Fluoro-4-nitrophenoxy)piperidine.
3-(2-Fluoro-4-nitrophenoxy)piperidine (CAS 1304078-01-0) is a high-purity analytical reference standard with the molecular formula C11H13FN2O3 and a molecular weight of 240.23 g/mol.
The molecular framework of 3-(2-Fluoro-4-nitrophenoxy)piperidine (C11H13FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13FN2O3 |
| Molecular Weight | 240.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 1-(3-Fluoro-2-nitrophenyl)piperidin-4-ol (CAS 1286272-69-2)
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- 3-(3-Fluoro-4-nitrophenoxy)piperidine (CAS 1285572-27-1)
- 3-(3-Fluoro-5-hydroxyphenyl)-6,8-dioxabicyclo[3.2.1]Octan-3-ol (CAS 1313254-77-1)
- 7-Methoxy-1-methyl-9-(3-phenylpropyl)-9H-pyrido[3,4-b]indole (CAS 752212-78-5)
- 7-chloro-2-(methylsulfanyl)pyrido[2,3-d]pyrimidine (CAS 352328-41-7)
- 2-(1-Hydroxyethyl)-6-mercaptopyridine 1-oxide (CAS 100450-43-9)
- (5-Methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methanamine hydrochloride (CAS 105362-46-7)
- Ethyl 3-oxo-2-phenoxybutanoate (CAS 7699-83-4)
- 3-[(1H-1,2,3,4-tetrazol-5-yl)amino]benzoic acid (CAS 199535-07-4)
- 6-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 73778-92-4)
- 1-(4-Chlorophenyl)-3-(1-hydroxy-3-phenylpropan-2-yl)urea (CAS 338962-96-2)
- 2-(4-Methoxyphenyl)-5-phenyl-1H-imidazole-4-thiol (CAS 1325304-88-8)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
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