2-Hydroxy-2,2-diphenylacetohydrazide CAS 13050-38-9
| CAS No. | 13050-38-9 |
| Molecular Formula | C14H14N2O2 |
| Molecular Weight | 242.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Hydroxy-2,2-diphenylacetohydrazide (CAS 13050-38-9), molecular formula C14H14N2O2 and molecular weight 242.27 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, 2-Hydroxy-2,2-diphenylacetohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14N2O2 |
| Molecular Weight | 242.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- N1-(5-bromo-2-methoxybenzyl)-N3,N3-dimethylpropane-1,3-diamine (CAS 893598-23-7)
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- Ceritinib Impurity 59 (CAS CATO-C4X-104859)
- 2,5-Bis(2,3,5-trichlorophenyl)pyridin-4-amine (CAS 1361585-50-3)
- N-(3,4-Dimethoxyphenyl)-3-methylbenzamide (CAS 449177-39-3)
- (1S,5S)-3-Methyl-3,6-diazabicyclo[3.2.0]heptane dihydrochloride (CAS 2227197-80-8)
- (2Z)-2-(3,4-Dichlorophenyl)-3-[2-(methylsulfanyl)quinolin-3-yl]prop-2-enenitrile (CAS 1164470-40-9)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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