Zanamivir Impurity 1 CAS 130525-58-5
| CAS No. | 130525-58-5 |
| Molecular Formula | C18H24N4O10 |
| Molecular Weight | 456.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Zanamivir Impurity 1.
Zanamivir Impurity 1 (CAS 130525-58-5) is a high-purity analytical reference standard with the molecular formula C18H24N4O10 and a molecular weight of 456.40 g/mol.
Zanamivir Impurity 1 (C18H24N4O10) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H24N4O10 |
| Molecular Weight | 456.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 4 |
Related Zanamivir Standards
- Zanamivir Amine Triacetate Methyl Ester (CAS 139110-70-6)
- Zanamivir Impurity 1 (CAS 313983-06-1)
- Zanamivir EP Impurity E (CAS CATO-C4X-20505)
- Zanamivir EP Impurity D (CAS 179531-53-4)
- Zanamivir EP Impurity H (CAS 179531-57-8)
- Zanamivir (CAS 139110-80-8)
- Zanamivir Impurity N (CAS 152178-79-5)
- Zanamivir EP Impurity C (CAS 130525-62-1)
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