1-Boc-4-fluoro-1H-indazole CAS 1305320-65-3
| CAS No. | 1305320-65-3 |
| Molecular Formula | C12H13FN2O2 |
| Molecular Weight | 236.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Boc-4-fluoro-1H-indazole (CAS 1305320-65-3) is a high-purity analytical reference standard with the molecular formula C12H13FN2O2 and a molecular weight of 236.24 g/mol.
1-Boc-4-fluoro-1H-indazole (C12H13FN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-Boc-4-fluoro-1H-indazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13FN2O2 |
| Molecular Weight | 236.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Boc Standards
- 4-fluoro-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (CAS 1093086-30-6)
- (3-Fluoro-5-methylfuran-2-yl)(2-methoxyphenyl)methanol (CAS 1282806-12-5)
- (3-Fluoro-4-methoxy-5-methylfuran-2-yl)(phenyl)methanol (CAS 1285283-25-1)
- 1-Boc-7-fluoro-1H-indazole (CAS 1305320-59-5)
- 1-[2-(2-fluoro-6-nitrophenyl)ethenyl]pyrrolidine (CAS 344790-94-9)
- Ethyl 8-fluoro-4-oxo-1,2,3,4-tetrahydronaphthalene-1-carboxylate (CAS 405196-40-9)
- Methyl 1-fluoro-5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulene-2-carboxylate (CAS 2114341-54-5)
- 2-Fluoro-4-(4-methylthiophenyl)benzoic acid (CAS 1261944-34-6)
Recommended Standards
- Methyl 2-amino-3-(4-fluoro-1H-indol-3-yl)propanoate (CAS 1313033-01-0)
- tert-Butyl (4-cyano-2-fluorophenyl)carbamate (CAS 1324000-27-2)
- 2,2-Difluoroethyl 4-methylbenzenesulfonate (CAS 135206-84-7)
- tert-Butyl (4-cyano-3-fluorophenyl)carbamate (CAS 1269523-39-8)
- 1-Methylindolin-6-amine dihydrochloride (CAS 1414958-31-8)
- (3-Bromo-2,4-dimethoxyphenyl)boronic acid (CAS 949146-53-6)
- Methyl 6-Bromo-2,6-dideoxy-α-D-ribo-hexopyranoside Dibenzoate (CAS 18933-67-0)
- 2-(2-Carboxyethyl)thio-4,6-dimethylpyrimidine 247225-29-2 8308AD C9H12N2O2S (CAS 247225-29-2)
- 4,6-Dichloro-1-nitroanthracene-9,10-dione (CAS 60506-83-4)
- (3-Fluoro-benzyl)-(2-trifluoromethylsulfanyl-ethyl)-amine (CAS 1208078-64-1)
- 8-Bromoquinolin-7-amine (CAS 208512-63-4)
- 4-(Furan-2-yl)-3-methylbenzoic acid (CAS 1261960-66-0)
- 1-Chloroethyl Ethyl Carbonate (CAS 50893-36-2)
- Biotinyl-Neuropeptide W-23 (human) (CAS 1815618-09-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com