5-Chloro-6-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine CAS 1305324-81-5
| CAS No. | 1305324-81-5 |
| Molecular Formula | C16H24ClIN2Si |
| Molecular Weight | 434.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Chloro-6-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1305324-81-5), molecular formula C16H24ClIN2Si and molecular weight 434.82 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-6-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (C16H24ClIN2Si) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H24ClIN2Si |
| Molecular Weight | 434.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-chloro-5-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1015609-83-2)
- 7-Chloro-5-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-c]pyridine (CAS 1198097-05-0)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(phenylcarbamoyl)amino]benzamide (CAS 1092343-35-5)
- 1-(4-Chloro-phenyl)-3-[4-(6-dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-urea (CAS 1311278-08-6)
- 1-(4-Chloro-phenyl)-3-[3-(6-dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-urea (CAS 1311280-16-6)
- 2-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-4-(1H-pyrrol-1-yl)isoindoline-1,3-dione (CAS 339101-76-7)
- Ethyl 5-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbonyl}-4,5-dihydro-1,2-oxazole-3-carboxylate (CAS 477864-85-0)
- 5-(3-Chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)-1-(1H-1,2,4-triazol-3-yl)indolin-2-one (CAS 1141080-15-0)
Recommended Standards
- 1,1,1,3,5,7,7,7-Octamethyl-3,5-diphenyltetrasiloxane (CAS 13270-97-8)
- 4-(Benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(5-methylisoxazol-3-yl)-1,5-dihydro-2H-pyrrol-2-one (CAS 618877-26-2)
- Halosulfuron-Methyl (CAS 100784-20-1)
- Disperse Violet 93 (Cl derivative) (CAS 66557-45-7)
- 6-(1-(Methoxyimino)ethyl)pyridin-2(1H)-one (CAS 195319-50-7)
- 5-((2-Fluorobenzyl)amino)-2-morpholinobenzoic acid (CAS 765925-11-9)
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- 2,4,6-Trichloro-3,5-dimethoxyaniline (CAS 2072084-91-2)
- Norepinephrine Impurity 111 (CAS 2947-04-8)
- 6-Heptyl-5,6-dihydro-2H-pyran-2-one (CAS 16400-72-9)
- 2-Methylfuran-3-ol (CAS 528825-07-2)
- (1S)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)methanol ((1S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate (CAS 60662-74-0)
- (R)-tert-Butyl 3-((5-methylpyridin-2-yl)thio)pyrrolidine-1-carboxylate (CAS 1354018-57-7)
- Endo-[Glu]31-Liraglutide (CAS CATO-C4X-199234)
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