4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}aniline hydrochloride CAS 1306605-05-9
| CAS No. | 1306605-05-9 |
| Molecular Formula | C12H9F3N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}aniline hydrochloride (CAS 1306605-05-9) is a high-purity analytical reference standard with the molecular formula C12H9F3N2OHCl and a molecular weight of 290.67 g/mol.
4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}aniline hydrochloride (C12H9F3N2OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}aniline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2O HCl |
| Molecular Weight | 290.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 3-(2-Methoxyethoxy)-1-propylamine (CAS 54303-31-0)
- Sodium phenyl acetate (CAS 114-70-5)
- 2-(3-(Pyrimidin-2-yl)phenyl)acetaldehyde (CAS 545423-80-1)
- 3-(Difluoromethyl)-6-fluoro-2-iodopyridin-4-amine (CAS 1806793-48-5)
- 6-(tert-Butyl)-4-cyclopropoxypicolinaldehyde (CAS 1243413-92-4)
- 2-Cyano-N-methyl-N-phenylacetamide (CAS 39581-30-1)
- 2-(2-Aminobenzo[d]oxazol-7-yl)acetic acid (CAS 1803740-24-0)
- 5-Phenylisothiazole-3-carboxylic acid (CAS 1732-46-3)
- Methyl 1,3-dibenzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 1335055-96-3)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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