4-((Tert-butyldiphenylsilyl)oxy)cyclohexan-1-one CAS 130745-59-4
| CAS No. | 130745-59-4 |
| Molecular Formula | C22H28O2Si |
| Molecular Weight | 352.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-((Tert-butyldiphenylsilyl)oxy)cyclohexan-1-one is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-((Tert-butyldiphenylsilyl)oxy)cyclohexan-1-one (CAS 130745-59-4), molecular formula C22H28O2Si and molecular weight 352.54 g/mol, is a CATO reference standard with documented purity and traceability.
4-((Tert-butyldiphenylsilyl)oxy)cyclohexan-1-one (C22H28O2Si) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H28O2Si |
| Molecular Weight | 352.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
Related Tert Standards
- 1-(((tert-Butyldiphenylsilyl)oxy)methyl)cyclobutane-1-carbaldehyde (CAS 956520-84-6)
- 5-(((tert-Butyldiphenylsilyl)oxy)methyl)-2-methyl-2H-tetrazole (CAS 2446073-21-6)
- 4-((tert-Butyldiphenylsilyl)oxy)hex-5-en-1-ol (CAS 113423-54-4)
- 3-((tert-Butyldiphenylsilyl)oxy)-2,2-difluoropropan-1-ol (CAS 1953133-33-9)
- 1-((tert-Butyldiphenylsilyl)oxy)-3-chloropropan-2-ol (CAS 1879071-16-5)
- 2-(((Tert-butyldiphenylsilyl)oxy)methyl)-1,3-dioxolan-4-one (CAS 145397-22-4)
- (3-(((Tert-butyldiphenylsilyl)oxy)methyl)oxetan-3-yl)methanol (CAS 1360106-23-5)
- 3-((tert-Butyldiphenylsilyl)oxy)-2,2-dimethylpropanoic acid (CAS 480450-04-2)
Recommended Standards
- (Z)-Methyl 7-(5-oxo-3-((triethylsilyl)-oxy)cyclopent-1-en-1-yl)hept-5-enoate (CAS 102494-28-0)
- (Z)-Methyl 7-(3-((tert-butyldimethylsilyl)oxy)-5-oxocyclopent-1-en-1-yl)hept-5-enoate (CAS 132619-70-6)
- 5-(1,3-Dioxolan-2-yl)-2-thienyl dodecyl ketone (CAS 898772-02-6)
- (1R,2R)-2-(((tert-Butyldiphenylsilyl)oxy)methyl)cyclobutane-1-carbaldehyde (CAS 2130069-72-4)
- (R)-8-Hydroxy-6-methoxy-3-methylisochroman-1-one (CAS 13410-15-6)
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- 2-(4-(Dimethylamino)benzyl)-3-oxoisoindoline-4-carboxylic acid (CAS 881041-36-7)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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