N-(4-Chloro-2-fluorophenyl)-2-hydroxybenzamide CAS 1308631-40-4
| CAS No. | 1308631-40-4 |
| Molecular Formula | C13H9ClFNO2 |
| Molecular Weight | 265.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 265.67 g/mol gives N-(4-Chloro-2-fluorophenyl)-2-hydroxybenzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(4-Chloro-2-fluorophenyl)-2-hydroxybenzamide (CAS 1308631-40-4) is a high-purity analytical reference standard with the molecular formula C13H9ClFNO2 and a molecular weight of 265.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(4-Chloro-2-fluorophenyl)-2-hydroxybenzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 265.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(4-Chloro-2-fluorophenyl)-2-hydroxybenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9ClFNO2 |
| Molecular Weight | 265.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
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- N-(3-CHloro-4-fluorophenyl)-3-hydroxybenzamide (CAS 1039809-17-0)
- Phenyl (4-chloro-3-fluorophenyl)carbamate (CAS 1229603-46-6)
- Methyl 5-(4-chloro-2-fluorophenyl)nicotinate (CAS 1346691-87-9)
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Recommended Standards
- 2-(3-Nitrophenoxy)ethane-1-sulfonyl chloride (CAS 1339388-84-9)
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- 4-Chloro-N-(3-(trifluoromethyl)phenyl)butanamide (CAS 300665-12-7)
- 1-(6-Chloro-4-(trifluoromethyl)pyridin-2-yl)piperazine (CAS 750628-50-3)
- N-hydroxy-5-methoxy-1H-indole-3-carboximidamide (CAS 889943-79-7)
- (4-Amino-3-chloro-5-(difluoromethyl)pyridin-2-yl)methanol (CAS 1805328-98-6)
- N-[(4-Fluorophenyl)methyl]-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbonyl)benzamide (CAS 861212-82-0)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(methylthio)pentanoic acid (CAS 1217832-67-1)
- N-(2-aminoethyl)-3-fluoro-4-methylbenzamide (CAS 950070-03-8)
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