4-(4-Methoxyphenoxy)tetrahydro-2H-pyran-4-carboxylic acid CAS 1308645-48-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1308645-48-8
Molecular FormulaC13H16O5
Molecular Weight252.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(4-Methoxyphenoxy)tetrahydro-2H-pyran-4-carboxylic acid CAS 1308645-48-8 chemical structure

Description

The occurrence of 4-(4-Methoxyphenoxy)tetrahydro-2H-pyran-4-carboxylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-(4-Methoxyphenoxy)tetrahydro-2H-pyran-4-carboxylic acid (CAS 1308645-48-8), molecular formula C13H16O5 and molecular weight 252.26 g/mol, is a CATO reference standard with documented purity and traceability.

4-(4-Methoxyphenoxy)tetrahydro-2H-pyran-4-carboxylic acid (C13H16O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H16O5
Molecular Weight252.26 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990

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