4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine CAS 1309377-79-4
| CAS No. | 1309377-79-4 |
| Molecular Formula | C6H6ClN3O |
| Molecular Weight | 171.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine.
CATO supplies 4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine (CAS 1309377-79-4), a certified reference material (molecular formula C6H6ClN3O, MW 171.58 g/mol) for analytical method development and quality control.
4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine (C6H6ClN3O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-6H,7H,8H-pyrimido[5,4-b][1,4]oxazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6ClN3O |
| Molecular Weight | 171.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-chloro-4-hydroxybenzamide (CAS 1007578-86-0)
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Recommended Standards
- 2-Chloro-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazine (CAS 1303587-99-6)
- Methyl 5-Chloro-2-pyridinecarboxylate (CAS 132308-19-1)
- 4-Chloro-5-(hydroxymethyl)picolinaldehyde (CAS 1289011-91-1)
- 5-Chloro-6-methoxynicotinaldehyde (CAS 132865-44-2)
- 4,4,6,6-Tetramethyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine (CAS 133667-41-1)
- 2-Phenylfuran, >95% (CAS 17113-33-6)
- Cis-3-methylenedecahydrocycloocta[b]furan (CAS 112701-82-3)
- 2-Bromo-N-(4-fluorobenzyl)butanamide (CAS 1119451-47-6)
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- 3-Isopropyl-4-methyl-1H-indazole (CAS 1415741-72-8)
- 3-Bromo-5-methoxybenzene-1-sulfonamide (CAS 1261438-84-9)
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- Ethyl 6-methyl-4-(phenylsulfanyl)-3-quinolinecarboxylate (CAS 477847-12-4)
- Insulin aspart (CAS 116094-23-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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