Ethyl 2,6-bis(difluoromethyl)-4-oxo-4H-pyran-3-carboxylate CAS 1309602-66-1
| CAS No. | 1309602-66-1 |
| Molecular Formula | C10H8F4O4 |
| Molecular Weight | 268.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethyl 2,6-bis(difluoromethyl)-4-oxo-4H-pyran-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ethyl 2,6-bis(difluoromethyl)-4-oxo-4H-pyran-3-carboxylate (CAS 1309602-66-1) is a high-purity analytical reference standard with the molecular formula C10H8F4O4 and a molecular weight of 268.16 g/mol.
The molecular framework of Ethyl 2,6-bis(difluoromethyl)-4-oxo-4H-pyran-3-carboxylate (C10H8F4O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F4O4 |
| Molecular Weight | 268.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Recommended Standards
- 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 1257553-99-3)
- (1-(3-Chlorophenyl)ethyl)(methyl)sulfamoyl chloride (CAS 1343356-66-0)
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- N-(2-Cyclopropoxy-5-methylphenyl)methanesulfonamide (CAS 1243400-38-5)
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- 2-Bromo-4-(chloromethyl)-5-(difluoromethyl)-3-methoxypyridine (CAS 1805424-12-7)
- 6,7-Dimethoxy-2-phenyl-4H-benzo[d][1,3]oxazin-4-one (CAS 31164-96-2)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
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