2-Amino-3-(trifluoromethyl)benzenethiol CAS 131105-90-3
| CAS No. | 131105-90-3 |
| Molecular Formula | C7H6F3NS |
| Molecular Weight | 193.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Amino-3-(trifluoromethyl)benzenethiol (CAS 131105-90-3), a certified reference material (molecular formula C7H6F3NS, MW 193.19 g/mol) for analytical method development and quality control.
The molecular framework of 2-Amino-3-(trifluoromethyl)benzenethiol (C7H6F3NS) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6F3NS |
| Molecular Weight | 193.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 1-Amino-5-(difluoromethyl)naphthalene (CAS 1261810-09-6)
- 1-Amino-4-(difluoromethyl)naphthalene (CAS 1261883-25-3)
- 2-amino-4-(trifluoromethyl)benzenethiol (CAS 19406-49-6)
- 1-amino-4-(difluoromethyl)cyclohexane-1-carboxylic acid (CAS 1955558-05-0)
- (S)-2-amino-2-(4,4-difluorocyclohexyl)acetic acid (CAS 1975200-03-3)
- (R)-2-amino-2-(4,4-difluorocyclohexyl)acetic acid (CAS 2231664-97-2)
- 2-Amino-2-(4,4-difluorocyclohexyl)acetic acid (CAS 769169-46-2)
- 2-Amino-5-(trifluoromethyl)benzenethiol (CAS 86691-07-8)
Recommended Standards
- Ethyl 3,3-difluoropiperidine-4-carboxylate (CAS 1303973-14-9)
- Methyl 2-(3,3-difluoropiperidin-4-yl)acetate (CAS 1334472-21-7)
- 2-(2,4-Difluorophenyl)-4-methyl-1H-pyrrole (CAS 1351486-83-3)
- 6-(Difluoromethyl)naphthalen-2-amine (CAS 1261844-91-0)
- Benzaldehyde-2,3,4,5,6-d5 (CAS 14132-51-5)
- 6-Chloroimidazo[2,1-b]thiazole (CAS 23576-81-0)
- 1,3-Dimethyl-2-methyleneimidazolidine (CAS 68738-47-6)
- Cefixime Impurity 18 (CAS CATO-C4X-113918)
- 4-Butyl-5-methyl-4h-1,2,4-triazole-3-thiol (CAS 19796-37-3)
- 161617-44-3 4-[1-(4-Iodophenyl)-5-(2,4-dinitrophenyl)-formaz-3-yl]-1,3-benzene Disulfonate, Disodium Salt 4-[[2-(2,4-Dinitrophenyl)hydrazinylidene][2-(4-iodophenyl)diazenyl]methyl]-1,3-benzenedisulfonic Acid Sodium Salt (CAS 161617-44-3)
- (R)-N-Boc-3-dimethylaminopiperidine (CAS 1061682-78-7)
- (3-Trifluoromethylsulfanyl-pyrazin-2-yl)-hydrazine (CAS 1286744-20-4)
- 1-(5-Chloro-2-hydroxy-3-(hydroxymethyl)phenyl)ethan-1-one (CAS 50317-52-7)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
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