[5-fluoro-2-(oxan-2-ylmethoxy)phenyl]boronic acid CAS 1311146-36-7
| CAS No. | 1311146-36-7 |
| Molecular Formula | C12H16BFO4 |
| Molecular Weight | 254.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
[5-fluoro-2-(oxan-2-ylmethoxy)phenyl]boronic acid (CAS 1311146-36-7), molecular formula C12H16BFO4 and molecular weight 254.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of [5-fluoro-2-(oxan-2-ylmethoxy)phenyl]boronic acid (C12H16BFO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), [5-fluoro-2-(oxan-2-ylmethoxy)phenyl]boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16BFO4 |
| Molecular Weight | 254.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
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