131123-44-9 (2S)-2-Amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid MFCD07371979 CAS 131123-44-9
| CAS No. | 131123-44-9 |
| Molecular Formula | C10H10F3NO3 |
| Molecular Weight | 249.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 131123-44-9 (2S)-2-Amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid MFCD07371979.
131123-44-9 (2S)-2-Amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid MFCD07371979 (CAS 131123-44-9) is a high-purity analytical reference standard with the molecular formula C10H10F3NO3 and a molecular weight of 249.19 g/mol.
The molecular framework of 131123-44-9 (2S)-2-Amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid MFCD07371979 (C10H10F3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10F3NO3 |
| Molecular Weight | 249.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- Methyl 4-amino-3-(2,2,2-trifluoroethoxy)benzoate (CAS 1096863-64-7)
- Methyl 3-amino-4-(2,2,2-trifluoroethoxy)benzoate (CAS 1096863-89-6)
- (S)-2-amino-3-(2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1103894-71-8)
- 2-Amino-3-(2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1218228-20-6)
- Methyl 2-amino-2-(2-(trifluoromethoxy)phenyl)acetate (CAS 1218713-63-3)
- (R)-3-Amino-3-(3-(trifluoromethoxy)phenyl)propanoic acid (CAS 1228558-79-9)
- (S)-3-Amino-3-(4-(trifluoromethoxy)phenyl)propanoic acid (CAS 1228560-97-1)
- (S)-3-Amino-3-(2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1228561-33-8)
Recommended Standards
- Methyl 3-[2-oxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl]propanoate (CAS 1281936-66-0)
- Methyl 3-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1-carboxylate (CAS 1358715-37-3)
- (S)-2-Amino-3,3,3-trifluoro-2-(4-methoxyphenyl)propanoic acid (CAS 1280716-87-1)
- 1-NItro-2-(propan-2-yloxy)-4-(trifluoromethyl)benzene (CAS 1369927-95-6)
- (2-Methyl-2-trifluoromethyl-[1,1-biphenyl]-4-yl)-carboxylic acid (CAS 473264-01-6)
- Ethyl (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienoate (CAS 56019-71-7)
- 3-Iodo-5-methoxy-1H-indazole-6-carboxylic acid (CAS 1227267-16-4)
- 3,4-Difluorobenzenesulfinic acid sodium salt (CAS 114336-38-8)
- 3-Bromo-2-chloro-4-fluoro-5-nitrotoluene (CAS 1707710-35-7)
- Posaconazole Impurity 27 (CAS CATO-C4X-120827)
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- Tolterodine impurity 33 (CAS CATO-C4X-176733)
- 5-Methyl-4-nitroimidazole (CAS 14003-66-8)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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