4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile CAS 1311275-24-7
| CAS No. | 1311275-24-7 |
| Molecular Formula | C7H3ClN4 |
| Molecular Weight | 178.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile.
CATO supplies 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile (CAS 1311275-24-7), a certified reference material (molecular formula C7H3ClN4, MW 178.58 g/mol) for analytical method development and quality control.
4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile (C7H3ClN4) contains a nitrile group, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClN4 |
| Molecular Weight | 178.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-1,3-benzoxazole-2-carbonitrile (CAS 1172606-59-5)
- 2-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile (CAS 1824287-31-1)
- 2-Chloro-5H-pyrrolo[3,2-d]pyrimidine-6-carbonitrile (CAS 1935335-48-0)
- 3-Chloro-1H-pyrazolo[4,3-c]pyridine-7-carbonitrile (CAS 93546-19-1)
- 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (CAS 24391-41-1)
- 5-Chloro-[1,2,4]triazolo[4,3-a]pyridine-3-carbonitrile (CAS 66999-73-3)
- 5-chloro-2-isocyanatobenzonitrile (CAS 64411-72-9)
- 5-Chloro-6-methylpyrazine-2,3-dicarbonitrile (CAS 72126-54-6)
Recommended Standards
- 4-Chloropyrrolo[2,1-f][1,2,4]triazine-5-carbonitrile (CAS 1263286-52-7)
- 5-Chloroimidazo[1,5-c]pyrimidine-7-carbonitrile (CAS 1352904-35-8)
- 6-Chloroimidazo[1,2-b]pyridazine-3-carbonitrile (CAS 123531-54-4)
- 2-Chlorobenzo[d]oxazole-4-carbonitrile (CAS 1372188-34-5)
- Manganese(III) Acetate Dihydrate (CAS 19513-05-4)
- N-(5-bromo-2-ethoxybenzyl)-4-iodoaniline (CAS 477887-04-0)
- 1-((6-Chloropyridin-2-yl)methyl)-1H-1,2,4-triazole-3-carbonitrile (CAS 1520473-28-2)
- Ruxolitinib Impurity 239 (CAS CATO-C4X-2058239)
- 4-(Difluoromethyl)-6-methyl-3-nitropicolinoyl chloride (CAS 1804881-95-5)
- 2-Bromo-3-fluoro-5-iodophenol (CAS 1804910-83-5)
- 3-(Pyridin-2-ylmethyl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603068-07-1)
- L-Leucine-3,3-d2 (CAS 362049-59-0)
- Ac-Tyr-NHMe (CAS 6367-14-2)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
Why CATO?
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