N-(4-(2-(dimethylamino)-5-(trifluoromethyl)pyridin-3-yl)benzyl)-N-methylglycine CAS 1311279-35-2
| CAS No. | 1311279-35-2 |
| Molecular Formula | C18H20F3N3O2 |
| Molecular Weight | 367.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(4-(2-(dimethylamino)-5-(trifluoromethyl)pyridin-3-yl)benzyl)-N-methylglycine (CAS 1311279-35-2), molecular formula C18H20F3N3O2 and molecular weight 367.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(4-(2-(dimethylamino)-5-(trifluoromethyl)pyridin-3-yl)benzyl)-N-methylglycine (C18H20F3N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20F3N3O2 |
| Molecular Weight | 367.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-[3-(2-Dimethylamino-5-trifluoromethyl-pyridin-3-yl)-phenyl]-2-ethoxy-acetamide (CAS 1311278-24-6)
- {[4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzyl]-methyl-amino}-acetic acid (CAS 1311278-83-7)
- N-(3-(6-(dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)benzyl)-N-methylglycine (CAS 1311279-02-3)
- {[3-(2-Dimethylamino-5-trifluoromethyl-pyridin-3-yl)-benzyl]-methyl-amino}-acetic acid (CAS 1311279-74-9)
- N-(2-(dimethylamino)ethyl)-2-oxo-1-(3-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide (CAS 338754-92-0)
- N-{1-({2-[(Dimethylamino)methylene]hydrazino}carbonyl)-2-[(4-methyl-2-pyrimidinyl)amino]vinyl}benzenecarboxamide (CAS 339010-35-4)
- {3-[(Dimethylamino)sulfonyl]-6-oxo-6,6a,7,8,9,10-hexahydro-5H-pyrido[1,2-a]quinoxalin-5-yl}acetic acid (CAS 1101836-50-3)
- (Z)-4-(4-(dimethylamino)benzylidene)-2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one (CAS 39143-18-5)
Recommended Standards
- Methyl (E)-3-((3,4-difluorophenyl)amino)-2-(m-tolylsulfonyl)acrylate (CAS 1327173-72-7)
- 3,5-Bis(5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)pyridine (CAS 1373134-49-6)
- Boc-L-2-amino-6-(O,O-diethyl-phosphono)hexanoicacid (CAS 1217810-32-6)
- 2-(1-((5,7-Difluorobenzo[d]thiazol-2-yl)methyl)-4,5-dimethyl-6-oxo-1,6-dihydropyridazin-3-yl)acetic acid (CAS 140926-46-1)
- 4,4',4'',4''',4'''',4'''''-(5,6,7,8,13,14,15,16,21,22,23,24-Dodecadehydrotribenzo[a,g,m]cyclooctadecene-2,3,10,11,18,19-hexayl)hexakis[benzoicacid] (CAS 1670923-95-1)
- 6-Chloro-3-iodoquinolin-4(1H)-one (CAS 1330754-24-9)
- Tert-butyl (S)-((4-methylmorpholin-2-yl)methyl)carbamate (CAS 2382404-19-3)
- 1-Oxo-2-(3-(trifluoromethyl)phenyl)-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid (CAS 1005068-67-6)
- 3',4'-Dihydrospiro[piperidine-4,2'-pyrano[3,2-c]pyridine] (CAS 1824281-31-3)
- 2-Bromo-5-(difluoromethyl)-4-fluoronicotinic acid (CAS 1804637-56-6)
- Azetidin-3-ylmethanamine (CAS 116770-48-0)
- (3S,4S,5R,6R)-4-fluoro-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,5-triol (CAS 7226-70-2)
- Tert-butyl 4-(aminomethyl)-2,2-dimethylpiperidine-1-carboxylate (CAS 1534465-74-1)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com