(E)-3-(4-(6-(dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)phenyl)acrylic acid CAS 1311283-88-1
| CAS No. | 1311283-88-1 |
| Molecular Formula | C17H15F3N2O2 |
| Molecular Weight | 336.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-3-(4-(6-(dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)phenyl)acrylic acid (CAS 1311283-88-1) is a high-purity analytical reference standard with the molecular formula C17H15F3N2O2 and a molecular weight of 336.31 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (E)-3-(4-(6-(dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)phenyl)acrylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 336.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-3-(4-(6-(dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)phenyl)acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15F3N2O2 |
| Molecular Weight | 336.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- (E)-3-[3-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-acrylic acid (CAS 1311284-01-1)
- 4-[(Dimethylamino)methylene]-2-(4-nitrophenyl)-5-phenyl-2,4-dihydro-3H-pyrazol-3-one (CAS 1164515-07-4)
- 2-(4-(Dimethylamino)styryl)-6-nitroquinazolin-4(1H)-one (CAS 63441-07-6)
- N-(4-((Dimethylamino)methyl)benzyl)-4-(trifluoromethyl)benzamide (CAS 869632-29-1)
- 2-(2-(Dimethylamino)ethyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid (CAS 112392-95-7)
- (2E)-3-(Dimethylamino)-2-[(E)-2-(4-ethoxyphenoxy)benzoyl]prop-2-enenitrile (CAS 866152-26-3)
- N1-(2-(Dimethylamino)-2-(4-fluorophenyl)ethyl)-N2-(thiazol-2-yl)oxalamide (CAS 941871-17-6)
- 1-(2-(Dimethylamino)ethyl)-3-(4-(2-(2-(dimethylamino)ethyl)-1-formylhydrazinyl)phenyl)urea (CAS 1024164-18-8)
Recommended Standards
- 4-(2-Morpholin-4-yl-5-trifluoromethyl-pyridin-3-yl)-benzaldehyde (CAS 1311279-52-3)
- 3-(2-Morpholin-4-yl-5-trifluoromethyl-pyridin-3-yl)-benzaldehyde (CAS 1311278-45-1)
- N-(4-Fluoro-3-(trifluoromethyl)phenyl)-5-oxo-1,4-thiazepane-3-carboxamide (CAS 1396631-75-6)
- 1241674-84-9 2-({[3-(Trifluoromethyl)phenyl]amino}methyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3-dione MFCD17069387 (CAS 1241674-84-9)
- 1-(4-(4-Methoxyphenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 321848-16-2)
- 2-Hydroxyethyl carbamate (CAS 5395-01-7)
- (2-(Pyrrolidin-1-yl)pyridin-3-yl)methanamine hydrochloride (CAS 1588441-33-1)
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- Methyl 2-(4-(4-(thiophen-2-yl)pyrimidin-2-yl)phenoxy)propanoate (CAS 477856-51-2)
- N-(2-(4-Bromo-2-fluorophenoxy)ethyl)cyclohexanamine (CAS 1283004-33-0)
- Rivaroxaban Impurity 43 (CAS 1369969-44-7)
- 4,6-Dichloro-3-methyl-1H-indole-2-carboxylic acid (CAS 441801-00-9)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
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