2-[4-(difluoromethoxy)-3-methoxyphenyl]ethan-1-amine hydrochloride CAS 1311315-36-2
| CAS No. | 1311315-36-2 |
| Molecular Formula | C10H13F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-[4-(difluoromethoxy)-3-methoxyphenyl]ethan-1-amine hydrochloride (C10H13F2NO2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 253.67 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-[4-(difluoromethoxy)-3-methoxyphenyl]ethan-1-amine hydrochloride (CAS 1311315-36-2) is a high-purity analytical reference standard with the molecular formula C10H13F2NO2HCl and a molecular weight of 253.67 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13F2NO2 HCl |
| Molecular Weight | 253.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related difluoromethoxy Standards
- 2-(2-(Difluoromethoxy)phenyl)ethan-1-ol (CAS 1000533-82-3)
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Recommended Standards
- 2-ethyl-1-(2-methoxyethyl)piperazine (CAS 1315367-66-8)
- N-Cyclohexyl 1-BOC-piperidine-4-carboxamide (CAS 757949-48-7)
- 2-Amino-5-[[[(1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl]amino]methyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one Dihydrochloride 86496-18-6 Queuine Dihydrochloride [1S-(1|A,4|A,5|A)]-2-Amino-5-[[(4,5-dihydroxy-2-cyclopenten-1-yl)amino]methyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one Dihydrochloride (CAS 86496-18-6)
- Trans-3a,4,5,6,7,8,9,9a-octahydrocycloocta[d]isoxazole (CAS 61080-95-3)
- 3-(3-Methylisoxazol-5-yl)-2-(4-nitrophenyl)quinazolin-4(3H)-one (CAS 90059-42-0)
- (1R,2R)-2-(1-Methyl-1H-pyrazol-4-yl)cyclopropane-1-carboxylic acid (CAS 1820569-90-1)
- 3-Hydroxy-2-methylbutanoic Acid (CAS 473-86-9)
- 2-(3-Bromobenzoyl)-6-fluorobenzonitrile (CAS 1227162-77-7)
- Isavuconazole Impurity 100 Iodization HCl (CAS CATO-C4X-1236100)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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