Tert-butyl 3-amino-5-(trifluoromethyl)piperidine-1-carboxylate CAS 1312806-22-6
| CAS No. | 1312806-22-6 |
| Molecular Formula | C11H19F3N2O2 |
| Molecular Weight | 268.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tert-butyl 3-amino-5-(trifluoromethyl)piperidine-1-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Tert-butyl 3-amino-5-(trifluoromethyl)piperidine-1-carboxylate (CAS 1312806-22-6), molecular formula C11H19F3N2O2 and molecular weight 268.28 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Tert-butyl 3-amino-5-(trifluoromethyl)piperidine-1-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H19F3N2O2 |
| Molecular Weight | 268.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (3R,4S)-4-amino-3-(trifluoromethyl)piperidine-1-carboxylate (CAS 1283107-75-4)
- Tert-butyl (3R,5R)-3-amino-5-(trifluoromethyl)piperidine-1-carboxylate (CAS 1312810-24-4)
- tert-butyl 6-(trifluoromethyl)-1,4-diazepane-1-carboxylate (CAS 1273564-15-0)
- (3S,5R)-tert-Butyl 3-amino-5-(trifluoromethyl)piperidine-1-carboxylate (CAS 1312810-30-2)
- 4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide 52061-51-5 N,N-Dimethyl-|A-oxo-4-(phenylmethoxy)-1H-indole-3-acetamide (CAS 52061-51-5)
- 3-(1-Oxoisoindolin-2-yl)-3-(thiophen-2-yl)propanoic acid (CAS 478079-05-9)
- CPL-1 (CAS 220578-75-6)
- 1-(2-Chloro-6-fluorophenyl)cyclopropanecarbonitrile (CAS 124276-45-5)
- Ethyl 3-(4-(2-((2-bromo-4-methylphenyl)amino)-2-oxoethoxy)-3-ethoxyphenyl)-2-cyanoacrylate (CAS 333766-63-5)
- (S,5Z,8Z,11Z,13E,17Z)-Ethyl 15-hydroxyicosa-5,8,11,13,17-pentaenoate (CAS 1667760-39-5)
- tert-Butyl N-[(3R,4R)-4-fluoropyrrolidin-3-yl]carbamate (CAS 213388-71-7)
- 5-Iodo-2-(trifluoromethyl)benzaldehyde (CAS 1261827-15-9)
- Ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-[({3-cyano-5H,6H,7H,8H,9H,10H-cycloocta[b]pyridin-2-yl}sulfanyl)methyl]-4H-pyran-3-carboxylate (CAS 316358-94-8)
- D-Pro31-Tirzepatide (CAS CATO-CPTD788905)
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